Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202648 | 0.87 | PNP (0.31) | DGAT1PNP | |
| SCHEMBL5213310 | 0.85 | DGAT1 (0.37) | DGAT1NPC1MYC | |
| SCHEMBL19404995 | 0.85 | DGAT1 (0.37) | DGAT1NPC1PNP | |
| SCHEMBL23123528 | 0.82 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL67815 | 0.81 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL3637817 | 0.81 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL26965213 | 0.81 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL16660842 | 0.81 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL10358805 | 0.80 | PNP (0.33) | PNP | |
| SCHEMBL1108608 | 0.80 | DGAT1 (0.34) | DGAT1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3829559-B1 | INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20260035359-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2026-02-05 | — | — | US | disclosed |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| US-12365674-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | MERCK SHARP & DOHME LLC (US) | 2025-07-22 | — | — | US | disclosed |
| US-12331044-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | MERCK SHARP & DOHME LLC (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4554933-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-05-21 | — | — | EP | disclosed |
| US-20250136570-A1 | HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| CN-119451949-A | Herbicidal imidazole compounds | 先正达农作物保护股份公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-3876928-B1 | INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION | MERCK SHARP & DOHME LLC (US) | 2024-10-23 | — | — | EP | disclosed |
| EP-4441033-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. (US) | 2024-10-09 | — | — | EP | disclosed |
| US-20050070588-A1 | Imidazolyl inhibitors of 15-lipoxygenase | BRISTOL-MYERS SQUIBB COMPANY | 2005-03-31 | — | — | US | disclosed |
| EP-1224180-B1 | SUBSTITUTED AZOLES | NOVARTIS AG (CH) | 2003-07-02 | — | — | EP | disclosed |
| US-6579874-B2 | P38 MAP kinase inhibitors; treating Tumor necrosis factor (TNF-alpha) and Interleukin-1 mediated diseases, such as rheumatoid arthritis; imidazole and oxazole derivatives | NOVARTIS AG (CH) | 2003-06-17 | — | — | US | disclosed |
| EP-1224180-A2 | SUBSTITUTED AZOLES | Novartis AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| EP-0748314-B1 | TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THE SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AVENTIS PHARMA SA (FR) | 2002-05-15 | — | — | EP | disclosed |
| US-20020049220-A1 | Substituted azoles | NOVARTIS AG (CH) | 2002-04-25 | — | — | US | disclosed |
| WO-2000063204-A2 | SUBSTITUTED AZOLES | NOVARTIS AG (CH) | 2000-10-26 | — | — | WO | disclosed |
| US-5807878-A | CARDIOVASCULAR DISORDERS | Uclaf, Roussel (FR) | 1998-09-15 | — | — | US | disclosed |
| EP-0748314-A1 | NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023791-A1 | NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1995-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035359-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | CBR3, CBR1, CLIC1 | DGAT1 919/4885NPC1 733/4885PNP 4149/4885 |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | TFPI, TFPI2, F11 | DGAT1 4152/4885NPC1 2027/4885PNP 4526/4885 |
| US-20050070588-A1 | Imidazolyl inhibitors of 15-lipoxygenase | ALOX15, ALOX5, ALOX15B | DGAT1 238/4885NPC1 909/4885PNP 2925/4885 |
| US-12331044-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | HDAC1, HDAC11, HDAC10 | DGAT1 4019/4885NPC1 1079/4885PNP 1018/4885 |
| US-12365674-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | HDAC1, HDAC11, HDAC3 | DGAT1 3991/4885NPC1 425/4885PNP 840/4885 |
| US-20250136570-A1 | HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | HDAC1, HDAC7, HDAC5 | DGAT1 1931/4885NPC1 762/4885PNP 3667/4885 |
| US-20020049220-A1 | Substituted azoles | MAPK1, MAPK4, MAP3K1 | DGAT1 2618/4885NPC1 3073/4885PNP 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.