Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515551 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAPOLBTDP1GAA | |
| SCHEMBL27496344 | 0.81 | PRKCI (0.58) | SMN1; SMN2NAPRTLMNAPOLBP2RX7 | |
| SCHEMBL93650 | 0.80 | GAA (0.48) | SMN1; SMN2NAPRTLMNAPOLBP2RX7 | |
| SCHEMBL28108390 | 0.80 | PARP1 (0.58) | SMN1; SMN2LMNAEGLN1KDM4ETSHR | |
| SCHEMBL2431130 | 0.78 | NSD2 (0.62) | SMN1; SMN2LMNAPOLBHDAC6KDM4E | |
| SCHEMBL107347 | 0.77 | P2RX7 (0.66) | NAPRTP2RX7KDM4ETDP1TSHR | |
| SCHEMBL26336052 | 0.77 | P2RX7 (0.43) | SMN1; SMN2NAPRTLMNAP2RX7KDM4E | |
| SCHEMBL28841192 | 0.76 | PARP1 (0.49) | SMN1; SMN2LMNAP2RX7TLR7KDM4E | |
| SCHEMBL107538 | 0.75 | NAPRT (0.67) | SMN1; SMN2NAPRTLMNAEGLN1KDM4E | |
| SCHEMBL29514689 | 0.75 | NAPRT (0.67) | SMN1; SMN2NAPRTLMNAEGLN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152077-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | Bayer CropScience AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008131861-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |