Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161745 | 0.81 | GAA (0.48) | GAAP2RX7PLK1LMNAPOLB | |
| SCHEMBL4766191 | 0.81 | P2RX7 (0.71) | GAAP2RX7PLK1LMNAPOLB | |
| SCHEMBL26336052 | 0.81 | P2RX7 (0.43) | GAAP2RX7LMNAKDM4ETDP1 | |
| SCHEMBL107347 | 0.81 | P2RX7 (0.66) | GAAP2RX7KDM4ETDP1L3MBTL1 | |
| SCHEMBL6653582 | 0.80 | CHIA (0.56) | P2RX7LMNAKDM4EL3MBTL1KMT2A | |
| SCHEMBL3634145 | 0.80 | SMN1; SMN2 (0.41) | GAAP2RX7LMNAPOLBKDM4E | |
| SCHEMBL26336039 | 0.80 | MAPK8 (0.48) | P2RX7LMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL19983228 | 0.79 | GAA (0.47) | GAAP2RX7PLK1LMNAPOLB | |
| SCHEMBL9569279 | 0.79 | GAA (0.47) | GAAP2RX7PLK1LMNAPOLB | |
| SCHEMBL1467988 | 0.79 | SMN1; SMN2 (0.61) | GAALMNAPOLBTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2425878-A1 | Protective coating compostition | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO (NL) | 2012-03-07 | — | — | EP | disclosed |