SCHEMBL363474

SCHEMBL363474

CC(C)(CN)OC(=O)C1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
TSHR P16473 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
PMP22 Q01453 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41
GABRG3 Q99928 1/20 0.41
GABRQ Q9UN88 1/20 0.41
NOS2 P35228 1/20 0.35
GNAI3 P08754 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16054755 0.98 GABRP (0.39) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL659836 0.91 MAPT (0.38) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL690050 0.91 MAPT (0.38) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL661356 0.91 MAPT (0.38) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL2423420 0.90 GABRP (0.38) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL4438483 0.87 GABRP (0.36) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL1376080 0.86 GABRP (0.41) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL16051286 0.86 GABRP (0.41) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL28056841 0.86 TSHR (0.41) GABRPGABRDGABRA1TSHRGABRB1
SCHEMBL2461649 0.85 CHRNB2 (0.36) NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4740955-A2 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2026-05-13 EP disclosed
EP-4702020-A1 PYRIDOIMIDAZOLONE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2026-03-04 EP disclosed
US-12421289-B2 GLP-1 analogues SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2025-09-23 US disclosed
US-20240376175-A1 Novel GLP-1 Analogues SUN PHARMACEUTICAL IND LTD (IN) 2024-11-14 US disclosed
WO-2024223905-A1 PYRIDOIMIDAZOLONE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-10-31 WO disclosed
EP-4433471-A1 N-(2H-INDAZOL-5-YL)PYRAZINE-2-CARBOXAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS HTT MODULATORS FOR THE TREATMENT OF HUNTINGTON'S DISEASE CHDI Foundation, Inc. (US) 2024-09-25 EP disclosed
US-20240199718-A1 GLP-1 Analogues SUN PHARMACEUTICAL IND LTD (IN) 2024-06-20 US disclosed
WO-2024097063-A1 POLYMORPHIC FORMS OF A SOLUBLE EPOXIDE HYDROLASE INHIBITOR AND FORMULATIONS THEREOF EICOSIS, LLC (US) 2024-05-10 WO disclosed
EP-4364751-A2 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2024-05-08 EP disclosed
CN-117964735-A Novel GLP-1 analogues 太阳医药工业有限公司 2024-05-03 CN disclosed
WO-2001064679-A1 1,5-DISUBSTITUTED-3,4-DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CSBP/P38 KINASE MEDIATED DISEASES SMITHKLINE BEECHAM CORPORATION (US) 2001-09-07 WO disclosed
EP-1080069-A1 ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-03-07 EP disclosed
WO-2000076970-A2 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2000-12-21 WO disclosed
WO-2000076971-A2 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2000-12-21 WO disclosed
WO-2000076972-A1 N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-12-21 WO disclosed
WO-2000076512-A1 CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-12-21 WO disclosed
WO-2000059498-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed
EP-1003514-A1 CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Merck & Co., Inc. (US) 2000-05-31 EP disclosed
WO-1999054284-A1 ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-28 WO disclosed
WO-1999004794-A1 CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376175-A1 Novel GLP-1 Analogues GLP1R, GIPR, GPR119 GABRP 417/4885GABRD 904/4885GABRA1 1243/4885
US-12421289-B2 GLP-1 analogues GLP1R, GIPR, GPR119 GABRP 308/4885GABRD 664/4885GABRA1 1106/4885
US-20240199718-A1 GLP-1 Analogues GLP1R, GIPR, GPR119 GABRP 308/4885GABRD 664/4885GABRA1 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.