Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635670 | 0.81 | F11 (0.36) | F11DGAT1 | |
| SCHEMBL3032289 | 0.80 | MAPT (0.31) | MAPT | |
| SCHEMBL13560488 | 0.78 | NPC1 (0.30) | MAPT | |
| SCHEMBL13560402 | 0.76 | — | — | |
| SCHEMBL13560540 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL3030125 | 0.74 | DUT (0.31) | — | |
| SCHEMBL1108611 | 0.71 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL3461380 | 0.70 | MAPK1 (0.32) | DGAT1 | |
| SCHEMBL23123528 | 0.70 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL3635281 | 0.69 | DGAT1 (0.35) | MAPTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |
| EP-2166856-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |