⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373408 | 0.74 | — | — | |
| SCHEMBL28818136 | 0.67 | — | — | |
| SCHEMBL27784702 | 0.65 | ALDH1A1 (0.38) | — | |
| SCHEMBL17261614 | 0.63 | MEN1 (0.42) | — | |
| SCHEMBL14080053 | 0.62 | KDM4E (0.35) | — | |
| SCHEMBL563542 | 0.62 | KDM4E (0.35) | — | |
| SCHEMBL9544601 | 0.62 | TRPA1 (0.33) | — | |
| SCHEMBL24611757 | 0.62 | EPHA4 (0.35) | — | |
| SCHEMBL4809415 | 0.61 | — | — | |
| SCHEMBL19504384 | 0.61 | ACHE (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143869-A1 | USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-2593093-A1 | USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE | Merz Pharma GmbH & Co. KGaA (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007560-A1 | USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-01-19 | — | — | WO | disclosed |