Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828886 | 0.90 | CA2 (0.38) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL9532045 | 0.79 | KMT2A (0.39) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL16539159 | 0.77 | CA1 (0.40) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL27420046 | 0.77 | KMT2A (0.38) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL17335572 | 0.77 | CA1 (0.40) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL20510151 | 0.75 | CA2 (0.47) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL3685916 | 0.74 | — | — | |
| SCHEMBL104865 | 0.74 | — | — | |
| SCHEMBL5323929 | 0.74 | KMT2A (0.45) | CA1CA2KMT2AALOX15BLM | |
| SCHEMBL29069596 | 0.74 | ALDH1A1 (0.46) | CA1CA2KMT2AALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170813-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | Satyanarayana Reddy, Manne (IN) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001372-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | SATYANARAYANA REDDY MANNE (IN) | 2008-12-31 | — | — | WO | disclosed |