Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846937 | 0.87 | KMT2A (0.46) | KMT2AALOX15BLMPMP22CHRNB2 | |
| SCHEMBL27420046 | 0.83 | KMT2A (0.38) | KMT2AALOX15BLMPMP22CHRNB2 | |
| SCHEMBL18222768 | 0.80 | LMNA (0.48) | KMT2AALOX15PMP22GABRPGABRD | |
| SCHEMBL20489977 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA4GABRPGABRD | |
| SCHEMBL1783594 | 0.80 | ALDH1A1 (0.43) | CHRNB2CHRNB4CHRNA4GABRPGABRD | |
| SCHEMBL25246790 | 0.80 | KMT2A (0.39) | KMT2AALOX15BLMPMP22CHRNB2 | |
| SCHEMBL3636048 | 0.79 | CA1 (0.38) | KMT2AALOX15BLMPMP22CHRNB2 | |
| SCHEMBL3685916 | 0.79 | — | — | |
| SCHEMBL104865 | 0.79 | — | — | |
| SCHEMBL5322012 | 0.78 | KMT2A (0.48) | KMT2AALOX15BLMPMP22FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |