Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623535 | 0.86 | MEN1 (0.51) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL3643682 | 0.84 | OPRD1 (0.49) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL2430851 | 0.76 | MEN1 (0.69) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL2430848 | 0.76 | MEN1 (0.69) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL9530935 | 0.71 | MEN1 (0.51) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL4243353 | 0.70 | OPRM1 (0.68) | OPRM1OPRL1OPRD1OPRK1CACNA2D1 | |
| Acetic Acid SCHEMBL11195893 | 0.69 | OPRD1 (0.61) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL4153276 | 0.69 | MEN1 (0.53) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL4153281 | 0.69 | MEN1 (0.53) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| Hydrochloric Acid SCHEMBL30961624 | 0.69 | OPRD1 (0.45) | OPRM1OPRL1OPRD1OPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2175856-A2 | NOVEL PROCESS FOR PREPARING HIGHLY PURE LEVOCETIRIZINE AND SALTS THEREOF | Chemagis Ltd. (IL) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009022327-A2 | NOVEL PROCESS FOR PREPARING HIGHLY PURE LEVOCETIRIZINE AND SALTS THEREOF | CHEMAGIS LTD. (IL) | 2009-02-19 | — | — | WO | disclosed |