Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.68 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.68 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.67 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.67 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 6/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620125 | 0.92 | CACNA2D1 (0.63) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL2430851 | 0.88 | MEN1 (0.69) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL9254374 | 0.88 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL2430848 | 0.88 | MEN1 (0.69) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL11386919 | 0.85 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL9258075 | 0.83 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL5541529 | 0.82 | CACNA2D1 (0.58) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 | |
| SCHEMBL5266144 | 0.82 | CACNA2D1 (1.00) | CACNA2D1CACNA1BCACNB1CACNA1GCACNA1C | |
| SCHEMBL3396514 | 0.81 | CACNA2D1 (1.00) | CACNA2D1CACNA1BCACNB1CACNA1GCACNA1C | |
| Acetic Acid SCHEMBL11195893 | 0.81 | OPRD1 (0.61) | OPRM1OPRD1OPRK1OPRL1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105260-A1 | Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105260-A1 | Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor | NOTUM, TRPV1, TRPV4 | OPRM1 1518/4885OPRD1 598/4885OPRK1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.