SCHEMBL3637178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL486067	0.83	KMO (0.59)	MAP4K4CYP4F2CYP4A11P4HA1MIF
	SCHEMBL28563936	0.83	DDT (0.61)	HSD17B1HSD17B2MAP4K4P4HA1MIF
	SCHEMBL29772925	0.83	DDT (0.61)	HSD17B1HSD17B2MAP4K4P4HA1MIF
	SCHEMBL29929320	0.82	HIF1A (0.55)	MAP4K4P4HA1MIFP4HTMKDM4E
	SCHEMBL71034	0.82	HIF1A (0.55)	MAP4K4P4HA1MIFP4HTMKDM4E
	SCHEMBL13680500	0.82	KMO (0.57)	HSD17B1HSD17B2MAP4K4CYP4F2CYP4A11
	SCHEMBL21552113	0.82	EGLN1 (0.58)	MAP4K4P4HTMESR2EGLN1
	SCHEMBL9939518	0.82	FTO (0.53)	HSD17B1HSD17B2CYP3A4CYP2C9MAP4K4
	SCHEMBL13731115	0.82	P4HTM (0.64)	CYP3A4MAP4K4P4HA1MIFP4HTM
	SCHEMBL11044314	0.80	P4HTM (0.53)	MAP4K4P4HA1MIFP4HTMESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.