Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.71 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.71 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | AKT2 | P31751 | 1/20 | 0.55 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636451 | 0.97 | OPRM1 (0.72) | OPRM1OPRL1OPRK1DRD4AKT1 | |
| SCHEMBL3665096 | 0.83 | OPRM1 (1.00) | OPRM1OPRL1OPRK1DRD4AKT1 | |
| SCHEMBL3741111 | 0.82 | CHRM2 (0.59) | OPRM1OPRL1OPRK1CHRM2CHRM4 | |
| SCHEMBL3758854 | 0.80 | OPRM1 (0.52) | OPRM1OPRL1OPRK1 | |
| SCHEMBL6591096 | 0.80 | OPRM1 (0.97) | OPRM1OPRL1OPRK1DRD4CHRM2 | |
| Oxalic Acid SCHEMBL5778025 | 0.79 | OPRM1 (0.91) | OPRM1OPRL1OPRK1DRD4AKT1 | |
| SCHEMBL8863557 | 0.79 | OPRM1 (0.91) | OPRM1OPRL1OPRK1DRD4AKT1 | |
| SCHEMBL4922697 | 0.79 | OPRM1 (1.00) | OPRM1OPRL1OPRK1DRD4CHRM2 | |
| SCHEMBL11223608 | 0.79 | OPRM1 (0.86) | OPRM1OPRL1OPRK1DRD4AKT1 | |
| SCHEMBL4913077 | 0.79 | OPRM1 (1.00) | OPRM1OPRL1OPRK1DRD4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |