Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.72 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.72 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | AKT2 | P31751 | 1/20 | 0.56 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.56 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637576 | 0.97 | OPRM1 (0.71) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL3665096 | 0.84 | OPRM1 (1.00) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL3758854 | 0.83 | OPRM1 (0.52) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL5778025 | 0.82 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL3751742 | 0.82 | CHRM2 (0.60) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL3751747 | 0.82 | CHRM2 (0.60) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL8863557 | 0.80 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL11223608 | 0.80 | OPRM1 (0.86) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL4679567 | 0.80 | OPRM1 (0.55) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL4679560 | 0.80 | OPRM1 (0.55) | OPRM1OPRK1OPRL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |