Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | YAP1 | P46937 | 4/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637824 | 1.00 | MEN1 (0.49) | MEN1KMT2AYAP1ITGB3ITGA2B | |
| SCHEMBL3642438 | 0.85 | MEN1 (0.54) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL3642645 | 0.85 | MEN1 (0.54) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL17822339 | 0.85 | ITGB3 (0.57) | MEN1KMT2AYAP1ITGB3ITGA2B | |
| SCHEMBL17822338 | 0.85 | ITGB3 (0.57) | MEN1KMT2AYAP1ITGB3ITGA2B | |
| SCHEMBL3641533 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL3641175 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL3642862 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL18114624 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL3642865 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| EP-2176217-B1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
| EP-2176217-A1 | AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009007696-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190725-A1 | AMINO ACID DERIVATIVES | NPR3, NPY4R, GFRA3 | MEN1 2615/4885KMT2A 1131/4885YAP1 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.