Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640350 | 0.90 | CCR2 (0.50) | CCR2MAPTNOD2NOD1KMT2A | |
| SCHEMBL13560628 | 0.86 | CCR2 (0.47) | CCR2MAPTNOD2NOD1KMT2A | |
| SCHEMBL28808282 | 0.84 | CCR2 (0.47) | CCR2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3638008 | 0.84 | NOD2 (0.53) | CCR2MAPTNOD2NOD1ELANE | |
| SCHEMBL29697822 | 0.83 | CCR2 (0.52) | CCR2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3023818 | 0.82 | NOD2 (0.48) | MAPTNOD2NOD1KMT2AMEN1 | |
| SCHEMBL10173095 | 0.81 | MAPT (0.45) | MAPTNOD2NOD1KMT2AMEN1 | |
| SCHEMBL3637426 | 0.80 | ABCB11 (0.45) | CCR2MAPTNOD2NOD1KMT2A | |
| SCHEMBL4421628 | 0.79 | NOD2 (0.60) | MAPTNOD2NOD1KMT2AMEN1 | |
| SCHEMBL1415761 | 0.79 | CCR2 (0.63) | CCR2MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166856-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |