Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984447 | 0.89 | SFRP1 (0.47) | CCR8GPR119IKBKBCHUKSFRP1 | |
| SCHEMBL2985375 | 0.82 | IKBKB (0.47) | IKBKBCHUKALDH1A1HTR1AHTR7 | |
| SCHEMBL2985378 | 0.81 | IKBKB (0.56) | IKBKBCHUKALDH1A1HTR1AHTR7 | |
| SCHEMBL13241047 | 0.75 | PTGDR2 (0.36) | — | |
| SCHEMBL2984105 | 0.73 | IKBKB (0.53) | IKBKBCHUKHTR1AHTR7 | |
| SCHEMBL2984107 | 0.73 | IKBKB (0.63) | IKBKBCHUK | |
| SCHEMBL3635894 | 0.72 | ALDH1A1 (0.54) | GPR119KDM4EHSD17B10F13A1TGM2 | |
| SCHEMBL3415802 | 0.72 | IKBKB (0.46) | IKBKBCHUKHTR1AHTR7 | |
| SCHEMBL3415805 | 0.71 | IKBKB (0.54) | IKBKBCHUKHTR1AHTR7 | |
| SCHEMBL3415349 | 0.69 | IKBKB (0.42) | IKBKBCHUKHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162455-A2 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | Glaxo Group Limited (GB) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008145688-A2 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | GLAXO GROUP LIMITED (GB) | 2008-12-04 | — | — | WO | disclosed |