SCHEMBL3638866

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4388169	0.94	RXRB (0.50)	RXRARXRBRXRGTPMTTP53
	SCHEMBL30056963	0.91	CES2 (0.48)	RXRARXRBRXRGSRD5A2ALDH1A1
	SCHEMBL21609834	0.91	CES2 (0.48)	RXRARXRBRXRGSRD5A2ALDH1A1
	SCHEMBL5005131	0.89	CA12 (0.50)	RXRARXRBRXRGTPMTTP53
	SCHEMBL5007948	0.89	TPMT (0.53)	RXRARXRBRXRGTPMTSMN1; SMN2
	SCHEMBL29448808	0.88	HCAR1 (0.46)	RXRARXRBRXRGTPMTHSD17B10
	SCHEMBL30055155	0.88	TPMT (0.52)	RXRARXRBTPMTALOX15HCAR1
	SCHEMBL12398885	0.88	NOTUM (0.41)	RXRARXRBRXRGTPMTSMN1; SMN2
	SCHEMBL3934869	0.88	HCAR1 (0.46)	RXRARXRBRXRGTPMTHSD17B10
	SCHEMBL26146854	0.88	TPMT (0.52)	RXRARXRBTPMTALOX15HCAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.