SCHEMBL3639192

SCHEMBL3639192

CCCCCC[PH](=O)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.46
PKM P14618 1/20 0.46
DNM1 Q05193 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KCNH2 Q12809 3/20 0.43
CETP P11597 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9120228 1.00 EPHX2 (0.46) EPHX2PKMDNM1ALDH1A1KCNH2
SCHEMBL27577709 0.98 EPHX2 (0.43) EPHX2PKMDNM1ALDH1A1KCNH2
SCHEMBL9120006 0.92 SMN1; SMN2 (0.43) EPHX2PKMDNM1ALDH1A1KCNH2
SCHEMBL11305880 0.84 TP53 (0.42) EPHX2PKMTP53SMN1; SMN2
SCHEMBL7600151 0.76 TP53 (0.46) EPHX2ALDH1A1TP53SMN1; SMN2
SCHEMBL1322 0.75 MAOB (0.46) EPHX2ALDH1A1TP53
SCHEMBL8637868 0.73 CES2 (0.41) EPHX2PKMDNM1ALDH1A1CETP
SCHEMBL27520002 0.73 CES2 (0.41) EPHX2PKMDNM1ALDH1A1CETP
SCHEMBL27519996 0.73 CES2 (0.41) EPHX2PKMDNM1ALDH1A1CETP
SCHEMBL9347727 0.73 CES2 (0.41) EPHX2PKMDNM1ALDH1A1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160356-A1 AQUEOUS COMPOSITION CONTAINING A SALT, MANUFACTURING PROCESS AND USE SOLVAY (Société Anonyme) (BE) 2010-03-10 EP disclosed
WO-2008152043-A1 AQUEOUS COMPOSITION CONTAINING A SALT, MANUFACTURING PROCESS AND USE Solvay (Société Anonyme) (BE) 2008-12-18 WO disclosed
CN-1324089-C Flame-retardant resin composition POLYPLASTICS CO (JP) 2007-07-04 CN disclosed
CN-1732232-A Flame-retardant resin composition POLYPLASTICS CO (JP) 2006-02-08 CN disclosed