SCHEMBL7600151

SCHEMBL7600151

CC[PH](=O)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
MAOB P27338 1/20 0.39
F2 P00734 1/20 0.38
PLG P00747 1/20 0.38
ELANE P08246 1/20 0.38
CTSG P08311 1/20 0.38
CMA1 P23946 1/20 0.38
CTRC Q99895 1/20 0.38
CALM1 P0DP23 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
EPHX2 P34913 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1B1 P15121 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1322 0.85 MAOB (0.46) TP53MAOBF2PLGELANE
SCHEMBL11305880 0.82 TP53 (0.42) TP53MAOBF2PLGELANE
SCHEMBL9120006 0.79 SMN1; SMN2 (0.43) TP53MAOBALDH1A1EPHX2SMN1; SMN2
SCHEMBL27577709 0.77 EPHX2 (0.43) TP53ALDH1A1EPHX2SMN1; SMN2
SCHEMBL9120228 0.76 EPHX2 (0.46) TP53ALDH1A1EPHX2SMN1; SMN2
SCHEMBL3639192 0.76 EPHX2 (0.46) TP53ALDH1A1EPHX2SMN1; SMN2
SCHEMBL9122325 0.75 TP53 (0.43) TP53MAOBF2PLGELANE
SCHEMBL8164540 0.74 ADRA1A (0.46) SMN1; SMN2
Butane SCHEMBL5417876 0.73 TP53 (0.42) TP53ALDH1A1TSHREPHX2CES2
SCHEMBL10308650 0.73 CA2 (0.38) TP53NPSR1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1075495-A None JP disclosed
EP-0743059-B1 Antibacterial oral composition for applying to dental implant areas COLGATE PALMOLIVE CO (US) 2002-12-04 EP disclosed
US-6096293-A APPLYING ORAL COMPOSITION CONTAINING 2,4-DI-TERT-BUTYL PHENOL TO TEETH COLGATE-PALMOLIVE COMPANY (US) 2000-08-01 US disclosed
EP-0676948-B1 ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION COLGATE PALMOLIVE CO (US) 2000-06-21 EP disclosed
US-5912274-A WATER INSOLUBLE NONCATIONIC ANTIBACTERIAL PHENOL CONTAINING, RELATIVE TO THE HYDROXYL GROUP, AN ALKYL OR CYCLOALKYL GROUP, PREFERABLY TERT.-BUTYL (T-BUTYL), IN THE 2-POSITION, AND SUBSTITUENTS IN ONE OR BOTH OF THE 4- AND 5-POSITIONS COLGATE-PALMOLIVE COMPANY (US) 1999-06-15 US disclosed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP disclosed
US-5776435-A DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-07-07 US disclosed
US-5728756-A BETA-STYRENEPHOSPHONIC ACID-VINYL PHOSPHONIC ACID COPOLYMER FOR ANTIPLAQUE COLGATE PALMOLIVE COMPANY (US) 1998-03-17 US disclosed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US disclosed
US-5686064-A MIXTURE INCLUDES TETRAALKALI METAL POLYPHOSPHATE AND TRICLOSAN; DENTIFRICES COLGATE PALMOLIVE COMPANY (US) 1997-11-11 US disclosed
US-5292526-A Macroemulsion of non-cationic antibacterial agent COLGATE-PALMOLIVE CO. (US) 1994-03-08 US disclosed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US disclosed
US-5275805-A Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants COLGATE-PALMOLIVE CO. 1994-01-04 US disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5192531-A Triclosan as a water insoluble noncationic additive for dentifrices COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5188821-A ANTIBACTERIAL ANTIPLAQUE ORAL COMPOSITION MOUTHWASH OR LIQUID DENTIFRICE COLGATE-PALMOLIVE COMPANY (US) 1993-02-23 US disclosed
US-5180578-A Adhesion to oral surfaces COLGATE-PALMOLIVE COMPANY (US) 1993-01-19 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US disclosed
JP-S6475495-A PRODUCTION OF OPTICALLY ACTIVE PHOSPHINE OXIDES UBE INDUSTRIES 1989-03-22 JP disclosed