Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27520002 | 1.00 | CES2 (0.41) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL27519996 | 1.00 | CES2 (0.41) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL9347727 | 1.00 | CES2 (0.41) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL27411391 | 1.00 | CES2 (0.41) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL29184852 | 0.98 | CES2 (0.40) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL5138546 | 0.98 | CES2 (0.39) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL6400882 | 0.92 | CES2 (0.37) | CES2CES1EPHX2PKMNAAA | |
| SCHEMBL27731628 | 0.76 | TSHR (0.44) | ALDH1A1 | |
| SCHEMBL2155213 | 0.73 | TP53 (0.38) | CES2CES1ALDH1A1 | |
| SCHEMBL3639192 | 0.73 | EPHX2 (0.46) | EPHX2PKMDNM1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | claimed |
| CN-105073951-B | Flame retardant composition, flame-retardant fiber treated with the flame retardant composition, and method for increasing adhesion of flame-retardant component to fiber using the flame-retardant composition | 株式会社ADEKA | 2017-08-15 | — | — | CN | disclosed |
| CN-105073951-A | Flame retardant composition, flame-retardant fiber treated with the flame retardant composition, and method for increasing adhesion of flame-retardant component to fiber using the flame-retardant composition | ADEKA CORP | 2015-11-18 | — | — | CN | disclosed |
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | disclosed |