SCHEMBL363928

SCHEMBL363928

O=C(O)c1cc(F)c(F)cc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ASPH Q12797 1/20 0.50
KDM8 Q8N371 1/20 0.50
NFE2L2 Q16236 1/20 0.50
ALB P02768 2/20 0.43
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
AKR1C2 P52895 2/20 0.41
AKR1C1 Q04828 2/20 0.41
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
CYP1A2 P05177 1/20 0.39
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
ACMSD Q8TDX5 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31258575 1.00 KEAP1 (0.50) KEAP1KDM4EASPHKDM8NFE2L2
Bromide SCHEMBL28745862 0.97 KEAP1 (0.48) KEAP1KDM4EASPHKDM8NFE2L2
Hydrochloric Acid SCHEMBL11035410 0.97 KEAP1 (0.48) KEAP1KDM4EASPHKDM8NFE2L2
SCHEMBL1713733 0.94 KDM4E (0.54) KEAP1KDM4EASPHKDM8NFE2L2
SCHEMBL5872835 0.92 KDM4E (0.52) KEAP1KDM4EASPHKDM8NFE2L2
SCHEMBL4830274 0.88 KEAP1 (0.54) KEAP1KDM4EASPHKDM8NFE2L2
SCHEMBL27617055 0.87 KEAP1 (0.50) KEAP1KDM4EASPHKDM8NFE2L2
Lithium SCHEMBL30497778 0.86 KEAP1 (0.52) KEAP1KDM4EASPHKDM8NFE2L2
SCHEMBL29045470 0.86 KEAP1 (0.52) KEAP1KDM4EASPHKDM8NFE2L2
Phenol SCHEMBL1704480 0.85 AKR1C2 (0.49) KEAP1KDM4EASPHKDM8NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1066 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634196-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES Momentive Performance Materials GmbH (DE) 2025-10-22 EP claimed
CN-117624198-B Rare earth complex and preparation method and application thereof 江西师范大学 2025-03-21 CN claimed
CN-119613699-A Method for removing perfluoro polyether acyl fluoride end group 南开大学 2025-03-14 CN claimed
CN-119414657-A Fluorine-containing titanium oxide nanoparticle photoresist material, preparation method thereof and application thereof in photoetching technology 山东大学 2025-02-11 CN claimed
WO-2024250497-A1 PHOTOELECTRIC DEVICE AND MANUFACTURING METHOD THEREFOR, AND DISPLAY APPARATUS TCL科技集团股份有限公司 2024-12-12 WO claimed
CN-119095455-A Photoelectric device, preparation method thereof and display device TCL科技集团股份有限公司 2024-12-06 CN claimed
CN-116178129-B Preparation method of 2,4, 5-trifluoro-benzoic acid 浙江永太科技股份有限公司 2024-11-29 CN claimed
CN-118290254-A Rare earth complex for zinc battery electrolyte and preparation method and application thereof 中国科学院赣江创新研究院 2024-07-05 CN claimed
WO-2024126692-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2024-06-20 WO claimed
CN-117624198-A Rare earth complex and preparation method and application thereof 江西师范大学 2024-03-01 CN claimed
EP-0385253-B1 PROCESS FOR PREPARING 2,4,5-TRIFLUOROBENZOIC ACID OCCIDENTAL CHEMICAL CORPORATION (US) 1993-09-29 EP claimed
US-5233085-A Dissolving in dipolar aprotic solvent in absence of catalyst and heating OCCIDENTAL CHEMICAL CORPORATION (US) 1993-08-03 US claimed
US-5196590-A Heating a trihalophthalimide compound, water, mineral acid OCCIDENTAL CHEMICAL CORPORATION (US) 1993-03-23 US claimed
EP-0431294-A2 Preparation of 2,4,5-trifluorobenzoic acid by decarboxylation of 3,4,6-trifluorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1991-06-12 EP claimed
WO-1990012780-A1 INTERMEDIATES FOR THE PRODUCTION OF 2,4,5-TRIFLUORBENZOYL FLUORIDE MALLINCKRODT, INC. (US) 1990-11-01 WO claimed
EP-0385253-A1 Process for preparing 2,4,5-trifluorobenzoic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-05 EP claimed
US-4935541-A Preparation of 2,4,5-trifluorobenzoic acid by decarboxylation of 3,4,6-trifluorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-06-19 US claimed
US-4876387-A FORMING AMINE SALT OF 4,5-DIFLUOROANTHRANILIC ACID, DIAZOTIZATION, DECOMPOSITION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-24 US claimed
EP-0164619-B1 2,4,5-TRIHALO OR 2,3,4,5-TETRAHALO BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THEM BAYER AG (DE) 1988-10-12 EP claimed
EP-0164619-A1 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them BAYER AG (DE) 1985-12-18 EP claimed