Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ASPH | Q12797 | 2/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045470 | 0.97 | KEAP1 (0.52) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| Lithium SCHEMBL30497778 | 0.97 | KEAP1 (0.52) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| Boric Acid SCHEMBL29160818 | 0.92 | KEAP1 (0.48) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL31258575 | 0.88 | KEAP1 (0.50) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL363928 | 0.88 | KEAP1 (0.50) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL1713733 | 0.88 | KDM4E (0.54) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL20353288 | 0.87 | KEAP1 (0.45) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL9853614 | 0.87 | KEAP1 (0.45) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| Hydrochloric Acid SCHEMBL11035410 | 0.86 | KEAP1 (0.48) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL1099458 | 0.86 | KEAP1 (0.48) | KEAP1NFE2L2KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496482-B | Fluorine-containing liquid crystal polyester with high thermal conductivity and low dielectric constant, and preparation method and application thereof | 中科院广州化学有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-118955474-A | Radioisotope carbon-14 labeled bard-calide and preparation method and application thereof | 浙江爱索拓标记医药科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118507163-A | High-strength low-temperature-resistant three-core flexible cable and preparation process thereof | 江阴凯博通信科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117855487-A | Preparation method of waterproof nano-coating current collector | 江阴纳力新材料科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-116526067-A | Metal phthalocyanine complex/carbon composite material modified lithium sulfur battery diaphragm and preparation method thereof | 陕西科技大学 | 2023-08-01 | — | — | CN | claimed |
| CN-116514649-A | Preparation method of 4, 5-difluorophthalic acid | 河南省科学院化学研究所有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-116496482-A | Fluorine-containing liquid crystal polyester with high thermal conductivity and low dielectric constant, and preparation method and application thereof | 中科院广州化学有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-112707807-B | Preparation method of 4, 5-difluorophthalic acid | 苏州当量生物医药有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112707807-A | Preparation method of 4, 5-difluorophthalic acid | 苏州金蚕新材料科技有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-105504249-B | A kind of fluorine-containing conjugated polyester resin of hydrolysis, the fluorine-containing copolyesters compound substrate membranes of hydrolysis and preparation method thereof | 四川东方绝缘材料股份有限公司 | 2017-09-12 | — | — | CN | claimed |
| CN-104530058-B | The preparation method of octafluoro substituted phthalocyanine | 天津大学 | 2016-09-14 | — | — | CN | claimed |
| CN-105542137-A | Multipolymer resin, multipolymer compound base film and preparation method of multipolymer compound base film | SICHUAN DONGFANG INSULATING MAT CO LTD | 2016-05-04 | — | — | CN | claimed |
| CN-105504249-A | Hydrolysis-resistant fluorine-containing copolyester resin, hydrolysis-resistant fluorine-containing copolyester composite basal membrane and preparation method thereof | SICHUAN DONGFANG INSULATING MAT CO LTD | 2016-04-20 | — | — | CN | claimed |
| CN-104530058-A | Method for preparing octafluoro-substituted phthalocyanine | UNIV TIANJIN | 2015-04-22 | — | — | CN | claimed |
| CN-104098858-A | Polymer matrix composite material and preparation method thereof | DONGGUAN HUAKE ELECTRONIC CO LTD | 2014-10-15 | — | — | CN | claimed |
| EP-0429848-A2 | Preparation of 3,4-difluorobenzoic acid by the decarboxylation of 4,5-difluorophthalic anhydride or 4,5-difluorophthalic acid | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-06-05 | — | — | EP | claimed |
| US-5003103-A | Decarboxylation, chlorodenitration, catalysis | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-26 | — | — | US | claimed |
| US-4994606-A | Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-19 | — | — | US | claimed |
| US-4937377-A | HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-06-26 | — | — | US | claimed |
| JP-2073044-A | — | — | None | — | — | JP | disclosed |
| JP-3161461-A | — | — | None | — | — | JP | disclosed |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-12559506-B2 | Indazole based compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| US-12358868-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20250215004-A1 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS (DE) | 2025-07-03 | — | — | US | disclosed |
| EP-4559521-A2 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin (DE) | 2025-05-28 | — | — | EP | disclosed |
| CN-120005216-A | Synthesis of fluorine functionalized metal organic framework and application of fluorine functionalized metal organic framework in adsorption of radioactive thorium | 井冈山大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| US-12286411-B2 | Indane derivatives for use in the treatment of bacterial infection | ANTABIO SAS (FR) | 2025-04-29 | — | — | US | disclosed |
| EP-4404931-B1 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | GEORG AUGUST UNIV GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS UNIVSMEDIZIN (DE) | 2025-04-09 | — | — | EP | disclosed |
| US-12247013-B2 | Indane derivatives for use in the treatment of bacterial infection | ANTABIO SAS (FR) | 2025-03-11 | — | — | US | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-116496482-B | Fluorine-containing liquid crystal polyester with high thermal conductivity and low dielectric constant, and preparation method and application thereof | 中科院广州化学有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119233820-A | Azo compounds for the treatment of fibrotic diseases | 乔治-奥古斯特-哥廷根公法基金会大学的大学医学院 | 2024-12-31 | — | — | CN | disclosed |
| US-20240409529-A1 | Methods of Manufacturing a Bifunctional Compound, Ultrapure Forms of the Bifunctional Compound, and Dosage Forms Comprising the Same | ARVINAS OPERATIONS, INC. (US) | 2024-12-12 | — | — | US | disclosed |
| CN-118955474-A | Radioisotope carbon-14 labeled bard-calide and preparation method and application thereof | 浙江爱索拓标记医药科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2024227701-A1 | PYRIDAZINE COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | Tietze Chemical Consulting UG (haftungsbeschränkt) (DE) | 2024-11-07 | — | — | WO | disclosed |
| EP-4458358-A1 | PYRIDAZINE COMPOUNDS FOR ANTIFIBROTIC THERAPY | Tietze Chemical Consulting UG (DE) | 2024-11-06 | — | — | EP | disclosed |
| US-20240360152-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2024-10-31 | — | — | US | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118507163-A | High-strength low-temperature-resistant three-core flexible cable and preparation process thereof | 江阴凯博通信科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20240269298-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-08-15 | — | — | US | disclosed |
| EP-4404931-A1 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin (DE) | 2024-07-31 | — | — | EP | disclosed |
| US-12043612-B2 | Methods of manufacturing a bifunctional compound, ultrapure forms of the bifunctional compound, and dosage forms comprising the same | ARVINAS OPERATIONS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043612-B2 | Methods of manufacturing a bifunctional compound, ultrapure forms of the bifunctional compound, and dosage forms comprising the same | ARVINAS OPERATIONS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043612-B2 | Methods of manufacturing a bifunctional compound, ultrapure forms of the bifunctional compound, and dosage forms comprising the same | ARVINAS OPERATIONS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240217962-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2024-07-04 | — | — | US | disclosed |
| CN-113166084-B | Indane derivatives for the treatment of bacterial infections | 安塔比奥公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118027041-A | BTK inhibitor ring derivative and preparation method and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11981683-B2 | Indazole based compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| CN-117855487-A | Preparation method of waterproof nano-coating current collector | 江阴纳力新材料科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-113166085-B | Indane derivatives for the treatment of bacterial infections | 安塔比奥公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4332100-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| EP-4308557-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117425646-A | Phosphono derivative, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-01-19 | — | — | CN | disclosed |
| US-20240016941-A1 | COMBINATION THERAPY | ANTABIO SAS (FR) | 2024-01-18 | — | — | US | disclosed |
| CN-113544130-B | BTK inhibitor ring derivative and preparation method and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20230406816-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA INC (US) | 2023-12-21 | — | — | US | disclosed |
| WO-2023222865-A1 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN (DE) | 2023-11-23 | — | — | WO | disclosed |
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| EP-3689868-B1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS INC (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116514649-A | Preparation method of 4, 5-difluorophthalic acid | 河南省科学院化学研究所有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116514649-A | Preparation method of 4, 5-difluorophthalic acid | 河南省科学院化学研究所有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116514649-A | Preparation method of 4, 5-difluorophthalic acid | 河南省科学院化学研究所有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116526067-A | Metal phthalocyanine complex/carbon composite material modified lithium sulfur battery diaphragm and preparation method thereof | 陕西科技大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-116496482-A | Fluorine-containing liquid crystal polyester with high thermal conductivity and low dielectric constant, and preparation method and application thereof | 中科院广州化学有限公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-3601224-B1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | ANTABIO SAS (FR) | 2023-07-05 | — | — | EP | disclosed |
| CN-110914238-B | Compounds as antibiotics | 安塔比奥公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-115996918-A | Method for producing a difunctional compound, ultrapure form of a difunctional compound and dosage form comprising said difunctional compound | 阿尔维纳斯运营股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230097358-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2023-03-30 | — | — | US | disclosed |
| EP-4146642-A1 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME | Arvinas Operations, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-4125883-A1 | COMBINATION THERAPY | Antabio SAS (FR) | 2023-02-08 | — | — | EP | disclosed |
| US-20230012321-A1 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| US-20230012321-A1 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| US-11542266-B1 | Substituted piperidines as BTK inhibitors | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-01-03 | — | — | US | disclosed |
| US-11542266-B1 | Substituted piperidines as BTK inhibitors | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-01-03 | — | — | US | disclosed |
| US-20220388984-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2022-12-08 | — | — | US | disclosed |
| WO-2022228547-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-11-03 | — | — | WO | disclosed |
| US-20220315575-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2022-10-06 | — | — | US | disclosed |
| WO-2022198112-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-112707807-B | Preparation method of 4, 5-difluorophthalic acid | 苏州当量生物医药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112707807-B | Preparation method of 4, 5-difluorophthalic acid | 苏州当量生物医药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112707807-B | Preparation method of 4, 5-difluorophthalic acid | 苏州当量生物医药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA, INC. | 2022-06-02 | — | — | US | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| US-20220112169-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2022-04-14 | — | — | US | disclosed |
| EP-3978496-A1 | BTK INHIBITOR RING DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2022-04-06 | — | — | EP | disclosed |
| US-20220007648-A1 | Biocidal Compound | ZHANG XINGCHEN (US) | 2022-01-13 | — | — | US | disclosed |
| WO-2021231174-A1 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| US-20210347748-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2021-11-11 | — | — | US | disclosed |
| CN-113544130-A | BTK inhibitor ring derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-10-22 | — | — | CN | disclosed |
| WO-2021191240-A1 | COMBINATION THERAPY | ANTABIO SAS (FR) | 2021-09-30 | — | — | WO | disclosed |
| CN-108502867-B | Fluorine and nitrogen doped carbon quantum dot and preparation method and application thereof | 南京慧基生物技术有限公司 | 2021-08-10 | — | — | CN | disclosed |
| EP-3856729-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2021-08-04 | — | — | EP | disclosed |
| EP-3856730-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2021-08-04 | — | — | EP | disclosed |
| CN-113166084-A | Indane derivatives for the treatment of bacterial infections | 安塔比奥公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113166085-A | Indane derivatives for the treatment of bacterial infections | 安塔比奥公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210139458-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2021-05-13 | — | — | US | disclosed |
| US-11000511-B2 | Chemical compounds as antibiotics | ANTABIO SAS (FR) | 2021-05-11 | — | — | US | disclosed |
| CN-112707807-A | Preparation method of 4, 5-difluorophthalic acid | 苏州金蚕新材料科技有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112707807-A | Preparation method of 4, 5-difluorophthalic acid | 苏州金蚕新材料科技有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112707807-A | Preparation method of 4, 5-difluorophthalic acid | 苏州金蚕新材料科技有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112457180-A | Preparation method of aromatic dicarboxylic acid derivative | 上海若济生物医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| WO-2020239103-A1 | BTK INHIBITOR RING DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020239103-A1 | BTK INHIBITOR RING DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2020-12-03 | — | — | WO | disclosed |
| EP-3689868-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas Operations, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |
| CN-111470961-A | Efficient synthesis method of halogenated 1, 3-indene diketone compounds | 南京欧纳壹有机光电有限公司 | 2020-07-31 | — | — | CN | disclosed |
| US-20200155509-A1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | ANTABIO SAS (FR) | 2020-05-21 | — | — | US | disclosed |
| US-10647698-B2 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | ARVINAS OPERATIONS, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| WO-2020064174-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| WO-2020064173-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3628666-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |
| CN-110914238-A | Compounds as antibiotics | 安塔比奥公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-3601224-A1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | Antabio SAS (FR) | 2020-02-05 | — | — | EP | disclosed |
| CN-109776767-A | The conjugated polymer and its synthetic method of a kind of diketone of aphthothiophenes containing difluoro electrophilic unit and application | 华南理工大学 | 2019-05-21 | — | — | CN | disclosed |
| WO-2018172423-A1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | ANTABIO SAS (FR) | 2018-09-27 | — | — | WO | disclosed |
| CN-108502867-A | fluorine, nitrogen-doped carbon quantum dot and its preparation method and application | 南京慧基生物技术有限公司 | 2018-09-07 | — | — | CN | disclosed |
| US-20180155322-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2018-06-07 | — | — | US | disclosed |
| WO-2018102725-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas, Inc. (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180072997-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY | 2018-03-15 | — | — | US | disclosed |
| CN-107771176-A | The inhibitor of human immunodeficiency virus replication | VIIV保健英国第五有限公司 | 2018-03-06 | — | — | CN | disclosed |
| EP-3286174-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2018-02-28 | — | — | EP | disclosed |
| CN-105504249-B | A kind of fluorine-containing conjugated polyester resin of hydrolysis, the fluorine-containing copolyesters compound substrate membranes of hydrolysis and preparation method thereof | 四川东方绝缘材料股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| WO-2016172425-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE (NO.5) LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |
| CN-104530058-B | The preparation method of octafluoro substituted phthalocyanine | 天津大学 | 2016-09-14 | — | — | CN | disclosed |
| CN-105542137-A | Multipolymer resin, multipolymer compound base film and preparation method of multipolymer compound base film | SICHUAN DONGFANG INSULATING MAT CO LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-105504249-A | Hydrolysis-resistant fluorine-containing copolyester resin, hydrolysis-resistant fluorine-containing copolyester composite basal membrane and preparation method thereof | SICHUAN DONGFANG INSULATING MAT CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-104530058-A | Method for preparing octafluoro-substituted phthalocyanine | UNIV TIANJIN | 2015-04-22 | — | — | CN | disclosed |
| CN-104098858-A | Polymer matrix composite material and preparation method thereof | DONGGUAN HUAKE ELECTRONIC CO LTD | 2014-10-15 | — | — | CN | disclosed |
| US-8569535-B2 | Substituted benzoylamino-indan-2-carboxylic acids and related compounds | SANOFI (FR) | 2013-10-29 | — | — | US | disclosed |
| US-8569535-B2 | Substituted benzoylamino-indan-2-carboxylic acids and related compounds | SANOFI (FR) | 2013-10-29 | — | — | US | disclosed |
| US-20100113462-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | US | disclosed |
| US-20100113462-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | US | disclosed |
| CN-100467458-C | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB CO LTD (FR) | 2009-03-11 | — | — | CN | disclosed |
| WO-2008151211-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | SANOFI-AVENTIS (FR) | 2008-12-11 | — | — | WO | disclosed |
| US-7442692-B2 | Indanyl-piperazine compounds | LES LABORATOIRES SERVIER (FR) | 2008-10-28 | — | — | US | disclosed |
| US-20060223830-A1 | Indanyl-piperazine compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-05 | — | — | US | disclosed |
| CN-1840527-A | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2006-10-04 | — | — | CN | disclosed |
| EP-1094053-B1 | Method of preparing fluoroaromatic compounds | ZELINSKY INST OF ORGANIC CHEMI (RU) | 2003-05-21 | — | — | EP | disclosed |
| EP-1094053-A1 | Method of preparing fluoroaromatic compounds | Zelinsky Institute of Organic Chemistry (RU) | 2001-04-25 | — | — | EP | disclosed |
| US-6008407-A | REACTING CHLOROTRIFLUOROETHYLENE AND 1,3-BUTADIENE TO PRODUCE CHLOROTRIFLUOROCYCLOHEXENES, DEHYDROHALOGENATING THE MIXTURE OF CYCLOHEXENES WITH PHASE TRANSFER CATALYST IN PRESENCE OF ALKALI METAL HYDROXIDE WITHOUT SOLVENT | ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY (RU) | 1999-12-28 | — | — | US | disclosed |
| EP-0741122-B1 | Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids | CLARIANT GMBH (DE) | 1999-08-25 | — | — | EP | disclosed |
| US-5739388-A | Process for the preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0608714-B1 | Process for preparing chlorinated 4,5-difluorobenzoic acids, -benzoic acid derivatives and -benzaldehyde | HOECHST AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0600317-B1 | Process for the preparation of halogenated benzoic acids | HOECHST AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| CN-1138023-A | Process for preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids | HOECHST AG (DE) | 1996-12-18 | — | — | CN | disclosed |
| EP-0741122-A1 | Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |
| US-5481032-A | Process for the preparation of halogenated benzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5473095-A | Catalytic chlorination of the 4,5-difluorobenzoic derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-05 | — | — | US | disclosed |
| US-5436368-A | Intermediates in the preparation of 4,5-difluoroanthranillic acid | PFIZER INC. (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0555283-B1 | INTERMEDIATES IN THE PREPARATION OF 4,5-DIFLUOROANTHRANILIC ACID | PFIZER (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0608714-A1 | Process for preparing chlorinated 4,5-difluorobenzoic acids, -benzoic acid derivatives and -benzaldehyde | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0600317-A1 | Process for the preparation of halogenated benzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0555283-A1 | INTERMEDIATES IN THE PREPARATION OF 4,5-DIFLUOROANTHRANILIC ACID. | PFIZER (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007822-A1 | INTERMEDIATES IN THE PREPARATION OF 4,5-DIFLUOROANTHRANILIC ACID | PFIZER INC. (US) | 1992-05-14 | — | — | WO | disclosed |
| JP-H03161461-A | PREPARATION OF 3,4-DIFLUOROBENZOIC ACID BY DECARBOXYLATION OF 4,5-DIFLUOROPHTHALIC ANHYDRIDE OR 4,5-DIFLUOROPHTHALIC ACID | OCCIDENTAL CHEM CORP | 1991-07-11 | — | — | JP | disclosed |
| EP-0429848-A2 | Preparation of 3,4-difluorobenzoic acid by the decarboxylation of 4,5-difluorophthalic anhydride or 4,5-difluorophthalic acid | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0429848-A2 | Preparation of 3,4-difluorobenzoic acid by the decarboxylation of 4,5-difluorophthalic anhydride or 4,5-difluorophthalic acid | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0429848-A2 | Preparation of 3,4-difluorobenzoic acid by the decarboxylation of 4,5-difluorophthalic anhydride or 4,5-difluorophthalic acid | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-06-05 | — | — | EP | disclosed |
| US-5003103-A | Decarboxylation, chlorodenitration, catalysis | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-5003103-A | Decarboxylation, chlorodenitration, catalysis | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-5003103-A | Decarboxylation, chlorodenitration, catalysis | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4994606-A | Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4994606-A | Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4994606-A | Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4937377-A | HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| US-4937377-A | HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| US-4937377-A | HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| JP-H0273044-A | DIFLUOROANTHRANILIC ACID AND PREPARATION THEREOF | SDS BIOTECH KK | 1990-03-13 | — | — | JP | disclosed |
| JP-H0273044-A | DIFLUOROANTHRANILIC ACID AND PREPARATION THEREOF | SDS BIOTECH KK | 1990-03-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (33 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240269298-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | EGFR, BLK, CSNK1A1L | KEAP1 4756/4885NFE2L2 4817/4885KDM4E 3501/4885 |
| US-20220315575-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | VHL, CRBN, MAPT | KEAP1 136/4885NFE2L2 1047/4885KDM4E 1390/4885 |
| US-20220112169-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ARG1, ELANE, INSR | KEAP1 1437/4885NFE2L2 855/4885KDM4E 3775/4885 |
| US-20210139458-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | KEAP1 105/4885NFE2L2 86/4885KDM4E 1438/4885 |
| US-20220007648-A1 | Biocidal Compound | BPGM, ACMSD, PGM2 | KEAP1 4870/4885NFE2L2 4844/4885KDM4E 1472/4885 |
| US-20060223830-A1 | Indanyl-piperazine compounds | HTR4, NR4A1, NR4A3 | KEAP1 1092/4885NFE2L2 907/4885KDM4E 1559/4885 |
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | KEAP1 110/4885NFE2L2 873/4885KDM4E 1112/4885 |
| US-12286411-B2 | Indane derivatives for use in the treatment of bacterial infection | ELANE, ARG1, INSRR | KEAP1 1584/4885NFE2L2 900/4885KDM4E 3917/4885 |
| US-20220388984-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | KEAP1 105/4885NFE2L2 86/4885KDM4E 1438/4885 |
| US-20200155509-A1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | MRPL21, CFTR, H1-0 | KEAP1 2049/4885NFE2L2 3580/4885KDM4E 2060/4885 |
| US-20240016941-A1 | COMBINATION THERAPY | CFTR, ABCB11, SLC26A4 | KEAP1 646/4885NFE2L2 2019/4885KDM4E 4573/4885 |
| US-20240360152-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | LRRK2, CRBN, MDM2 | KEAP1 280/4885NFE2L2 1076/4885KDM4E 1629/4885 |
| US-12559506-B2 | Indazole based compounds and associated methods of use | LRRK2, CRBN, CLK2 | KEAP1 1094/4885NFE2L2 2098/4885KDM4E 988/4885 |
| US-12043612-B2 | Methods of manufacturing a bifunctional compound, ultrapure forms of the bifunctional compound, and dosage forms comprising the same | PAICS, UGT1A1, PBRM1 | KEAP1 2214/4885NFE2L2 1882/4885KDM4E 773/4885 |
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | KEAP1 2588/4885NFE2L2 4094/4885KDM4E 2284/4885 |
| US-12358868-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | KEAP1 2588/4885NFE2L2 4094/4885KDM4E 2284/4885 |
| US-20240217962-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | VHL, CRBN, MAPT | KEAP1 136/4885NFE2L2 1047/4885KDM4E 1390/4885 |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | UBQLN2, UBQLN1, CRBN | KEAP1 193/4885NFE2L2 1541/4885KDM4E 525/4885 |
| US-20250215004-A1 | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES | COL1A1, COL14A1, COL2A1 | KEAP1 292/4885NFE2L2 360/4885KDM4E 1205/4885 |
| US-11000511-B2 | Chemical compounds as antibiotics | MRPL21, CFTR, H1-0 | KEAP1 2049/4885NFE2L2 3580/4885KDM4E 2060/4885 |
| US-11542266-B1 | Substituted piperidines as BTK inhibitors | BTK, BLK, SYK | KEAP1 1969/4885NFE2L2 3208/4885KDM4E 729/4885 |
| US-20240409529-A1 | Methods of Manufacturing a Bifunctional Compound, Ultrapure Forms of the Bifunctional Compound, and Dosage Forms Comprising the Same | PAICS, UGT1A1, PBRM1 | KEAP1 2214/4885NFE2L2 1882/4885KDM4E 773/4885 |
| US-11981683-B2 | Indazole based compounds and associated methods of use | LRRK2, CRBN, MDM2 | KEAP1 280/4885NFE2L2 1076/4885KDM4E 1629/4885 |
| US-20230097358-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | LRRK2, CRBN, MDM2 | KEAP1 280/4885NFE2L2 1076/4885KDM4E 1629/4885 |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | KEAP1 2588/4885NFE2L2 4094/4885KDM4E 2284/4885 |
| US-12247013-B2 | Indane derivatives for use in the treatment of bacterial infection | ELANE, ARG1, INSRR | KEAP1 1584/4885NFE2L2 900/4885KDM4E 3917/4885 |
| US-20100113462-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | CXCR5, CXCR1, CCR5 | KEAP1 3944/4885NFE2L2 1930/4885KDM4E 2918/4885 |
| US-20180072997-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2H, POLR2E | KEAP1 2487/4885NFE2L2 3087/4885KDM4E 2426/4885 |
| US-20230012321-A1 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME | PAICS, UGT1A1, PBRM1 | KEAP1 2214/4885NFE2L2 1882/4885KDM4E 773/4885 |
| US-20180155322-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | KEAP1 105/4885NFE2L2 86/4885KDM4E 1438/4885 |
| US-20210347748-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | INSR, INSRR, ARG1 | KEAP1 1205/4885NFE2L2 778/4885KDM4E 3766/4885 |
| US-20230406816-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | KEAP1 2588/4885NFE2L2 4094/4885KDM4E 2284/4885 |
| US-10647698-B2 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | MDM2, CRBN, VHL | KEAP1 105/4885NFE2L2 86/4885KDM4E 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.