SCHEMBL1713733

SCHEMBL1713733

O=C(O)c1cc(F)c(C(=O)O)cc1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
KEAP1 Q14145 2/20 0.54
ASPH Q12797 2/20 0.54
KDM8 Q8N371 2/20 0.54
NFE2L2 Q16236 1/20 0.54
ALB P02768 2/20 0.46
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
AKR1C2 P52895 2/20 0.43
AKR1C1 Q04828 2/20 0.43
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 1/20 0.43
CYP1A2 P05177 1/20 0.43
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
ACMSD Q8TDX5 2/20 0.39
NAPRT Q6XQN6 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363928 0.94 KEAP1 (0.50) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL31258575 0.94 KEAP1 (0.50) KDM4EKEAP1ASPHKDM8NFE2L2
Bromide SCHEMBL28745862 0.92 KEAP1 (0.48) KDM4EKEAP1ASPHKDM8NFE2L2
Hydrochloric Acid SCHEMBL11035410 0.92 KEAP1 (0.48) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL5872835 0.91 KDM4E (0.52) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL4830274 0.88 KEAP1 (0.54) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL4367594 0.87 KDM4E (0.45) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL6068628 0.87 DGAT1 (0.50) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL1418105 0.85 KDM4E (0.44) KDM4EKEAP1ASPHKDM8NFE2L2
SCHEMBL223134 0.85 KEAP1 (0.53) KDM4EKEAP1ASPHKDM8NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
CN-119608128-B Fluorine-modified porous framework crystal material, preparation method thereof and acetylene/carbon dioxide separation application 德州学院 2025-05-02 CN claimed
CN-119608128-A Fluorine-modified porous framework crystal material, preparation method thereof and acetylene/carbon dioxide separation application 德州学院 2025-03-14 CN claimed
CN-116493051-B Method for preparing UiO-66 encapsulated platinum nanoparticle compound by electrostatic attraction regulation and control and application 天津大学 2025-02-07 CN claimed
CN-118136938-A Polymer composite solid electrolyte, preparation method and application thereof 南方科技大学 2024-06-04 CN claimed
CN-118108955-A Hydrophobic layer material and preparation method thereof, perovskite solar cell and preparation method thereof 旗滨新能源发展(深圳)有限责任公司 2024-05-31 CN claimed
CN-116779704-B Photovoltaic module applying high-light-transmittance backboard material 宁波欧达光电有限公司 2024-04-16 CN claimed
CN-116779705-B Photovoltaic module with anti-dazzle composite film 宁波欧达光电有限公司 2024-03-26 CN claimed
CN-117209746-A Silane end capped polyether resin and preparation method and application thereof 江西蓝星星火有机硅有限公司 2023-12-12 CN claimed
CN-117013199-A Fluorinated MOFs-based diaphragm for dendrite-free lithium metal battery and preparation method thereof 广东工业大学 2023-11-07 CN claimed
CN-103510184-B Fluorine-containing PET-PBT (polyethylene terephthalate- polybutylene terephthalate) copolyester DTY (draw texturing yarn) fiber and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2015-07-01 CN claimed
CN-103467720-B Fluorine-containing poly(ethylene terephthalate) (PET)-poly(butylene terephthalate) (PBT) copolyester and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2015-07-01 CN claimed
CN-103526322-A Fluorine-containing PET (polyethylene terephthalate)-PTT (polytrimethylene terephthalate) copolyester FDY (fully drawn yarn) fiber and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2014-01-22 CN claimed
CN-103524723-A Fluorine polyester and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2014-01-22 CN claimed
CN-103510184-A Fluorine-containing PET-PBT (polyethylene terephthalate- polybutylene terephthalate) copolyester DTY (draw texturing yarn) fiber and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2014-01-15 CN claimed
CN-103467720-A Fluorine-containing poly(ethylene terephthalate) (PET)-poly(butylene terephthalate) (PBT) copolyester and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2013-12-25 CN claimed
CN-103469335-A Fluorinated polyester high-strength wear-resistant industrial yarn and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2013-12-25 CN claimed
CN-103469356-A Fluorine-containing PET-PET sheath-core composite fibers and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2013-12-25 CN claimed
CN-103467718-A Fluorine-containing PET-PTT copolyester and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2013-12-25 CN claimed
CN-103469355-A Fluorine-containing PET-PET blended fiber and preparation method thereof JIANGSU LIXIN CHEMICAL FIBER TECHNOLOGY CO LTD 2013-12-25 CN claimed