Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310050 | 0.87 | MAPT (0.48) | MAPTALDH1A1LMNASIRT6GPR119 | |
| SCHEMBL3635783 | 0.86 | SIRT6 (0.53) | MAPTALDH1A1LMNAPTGDRSIRT6 | |
| SCHEMBL2203701 | 0.80 | SIRT6 (0.61) | MAPTALDH1A1LMNAPTGDRSIRT6 | |
| SCHEMBL310495 | 0.80 | MAPT (0.48) | MAPTALDH1A1LMNASIRT6SMN1; SMN2 | |
| SCHEMBL309972 | 0.78 | MAPT (0.58) | MAPTALDH1A1LMNAPTGDRSIRT6 | |
| SCHEMBL311262 | 0.77 | MAPT (0.54) | MAPTALDH1A1LMNAPTGDRSIRT6 | |
| SCHEMBL3503718 | 0.77 | MAPT (0.43) | MAPTALDH1A1LMNAPTGDRSIRT6 | |
| SCHEMBL25262102 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1LMNASIRT6SMN1; SMN2 | |
| SCHEMBL517794 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1LMNASIRT6PLK1 | |
| SCHEMBL520097 | 0.76 | MAPT (0.54) | MAPTALDH1A1LMNASIRT6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |