Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.46 |
| ▸ | FES | P07332 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384688 | 0.83 | MAPT (0.70) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL3643014 | 0.80 | MAPT (0.58) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL945302 | 0.78 | MAPT (0.52) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL945105 | 0.72 | RAB9A (0.71) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL4916732 | 0.72 | NPC1 (0.74) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL944850 | 0.72 | KCNMA1 (0.57) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL345091 | 0.72 | KCNMA1 (0.67) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL3384383 | 0.71 | KCNMA1 (0.54) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL4898350 | 0.71 | MAPT (0.53) | MAPTKCNMA1KDM4EALDH1A1HPGD | |
| SCHEMBL3387532 | 0.71 | KCNMA1 (0.56) | MAPTKCNMA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735434-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2160393-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008144360-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | MAPT 1735/4885KCNMA1 1416/4885KDM4E 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.