Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639863 | 0.87 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29588162 | 0.87 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| Phosphine SCHEMBL15543212 | 0.86 | KDM4E (0.97) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL12325283 | 0.80 | KMT2A (1.00) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL20776032 | 0.79 | NPC1 (0.54) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL1284437 | 0.79 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29475390 | 0.79 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29808445 | 0.77 | SMN1; SMN2 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL22955293 | 0.77 | SMN1; SMN2 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL5334468 | 0.77 | RAB9A (0.82) | KDM4ENPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| EP-2170822-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | Luxembourg Bio Technologies Ltd. (IL) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | PHAX, GIPR, IAPP | KDM4E 4871/4885NPC1 3699/4885RAB9A 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.