Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | GSTA2 | P09210 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026214 | 0.86 | ALDH1A1 (0.32) | ALDH1A1NPC1MAPTHIF1ASMN1; SMN2 | |
| SCHEMBL15157836 | 0.80 | HTT (0.41) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL364008 | 0.79 | KDM4E (0.34) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL13171565 | 0.75 | CA2 (0.41) | ALDH1A1KDM4ENPC1LMNAMAPT | |
| SCHEMBL29503697 | 0.71 | TACR1 (0.47) | ALDH1A1SLC1A3SLC1A2SLC1A1CACNA1B | |
| SCHEMBL2619047 | 0.71 | TACR1 (0.47) | ALDH1A1SLC1A3SLC1A2SLC1A1CACNA1B | |
| SCHEMBL1324374 | 0.71 | CA2 (0.43) | ALDH1A1KDM4ENPC1LMNAMAPT | |
| SCHEMBL25106661 | 0.70 | GPR84 (0.39) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL15157837 | 0.70 | ATM (0.35) | ALDH1A1KDM4EMEN1NPC1MAPT | |
| SCHEMBL15020074 | 0.70 | TACR1 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| EP-1753838-B1 | POLYMERISABLE NAPHTHOPYRAN DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM SAID DERIVATIVES | POLYMEREXPERT S A (FR) | 2012-03-14 | — | — | EP | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | CCND3, H1-3, H1-0 | ALDH1A1 1397/4885KDM4E 2000/4885MEN1 2826/4885 |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | C1S, H1-0, H1-3 | ALDH1A1 1029/4885KDM4E 3155/4885MEN1 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.