Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289409 | 0.86 | USP2 (0.56) | USP2KMT2AMEN1PKMTSHR | |
| SCHEMBL7434260 | 0.86 | USP2 (0.56) | USP2KMT2AMEN1PKMTSHR | |
| SCHEMBL14537720 | 0.83 | TSHR (0.75) | USP2KMT2AMEN1PKMTSHR | |
| SCHEMBL10210776 | 0.82 | NPC1 (0.74) | USP2KMT2AMEN1PKMTSHR | |
| SCHEMBL8251278 | 0.79 | REV1 (0.67) | USP2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL18177336 | 0.79 | ALDH1A1 (0.91) | USP2KMT2ANPC1ALDH1A1TDP1 | |
| SCHEMBL4777614 | 0.79 | KDM4E (0.69) | USP2KMT2AMEN1PKMNPC1 | |
| SCHEMBL22407743 | 0.79 | KDM4E (0.69) | USP2KMT2AMEN1PKMNPC1 | |
| SCHEMBL22777886 | 0.79 | KDM4E (0.94) | USP2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL6795359 | 0.79 | ALDH1A1 (0.94) | KMT2AMEN1NPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164491-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | Euroscreen S.A. (BE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009010477-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |