Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712690 | 0.84 | APLNR (0.72) | APLNRTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL28279207 | 0.77 | TP53 (0.67) | APLNRTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5543280 | 0.74 | APLNR (0.59) | APLNRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL568210 | 0.74 | SMN1; SMN2 (0.47) | APLNRTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL5542552 | 0.73 | APLNR (0.53) | APLNRMEN1KMT2APOLBHTR2A | |
| SCHEMBL28415525 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CA1CA2HPGDCA12 | |
| SCHEMBL20286051 | 0.72 | APLNR (0.53) | APLNRMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL28043790 | 0.72 | APLNR (0.69) | APLNRTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL350875 | 0.71 | ALDH1A1 (0.58) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8724130 | 0.71 | APLNR (0.73) | APLNRTP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173743-A2 | SODIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | disclosed |