SCHEMBL364082

SCHEMBL364082

Cc1c(C)c(CCC(=O)O)c(C)c(CCC(=O)O)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.46
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KEAP1 Q14145 1/20 0.39
GAA P10253 2/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
IMPDH2 P12268 3/20 0.39
EGFR P00533 2/20 0.39
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
FFAR3 O14843 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720879 0.98 NPSR1 (0.45) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL2919515 0.97 NPSR1 (0.48) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL28830916 0.95 NPSR1 (0.50) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL25934782 0.78 NPSR1 (0.41) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL25934779 0.78 NPSR1 (0.41) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL11370413 0.73 NPSR1 (0.37) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL547346 0.73 HSD17B10 (0.51) NPSR1HSD17B10KDM4EALDH1A1EGFR
SCHEMBL12042065 0.70 AKR1B1 (0.41) HSD17B10KDM4EGAAALDH1A1GLA
SCHEMBL30951419 0.70 HSD17B10 (0.39) NPSR1HSD17B10KDM4ENPC1RAB9A
SCHEMBL7695445 0.70 IMPDH2 (0.49) IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013033245-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-03-07 WO claimed
CN-118459390-B 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof SUN YAT-SEN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-120077106-A Curable composition, cured film, and display device 住友化学株式会社 2025-05-30 CN disclosed
CN-119110826-A Composition, film and display device 住友化学株式会社 2024-12-10 CN disclosed
CN-118946831-A Composition, film and display device 住友化学株式会社 2024-11-12 CN disclosed
CN-118852145-A GSPT1 degradation agent and application thereof 南京圣和药业股份有限公司 2024-10-29 CN disclosed
CN-118786366-A Composition, protective layer, laminate, and display device 住友化学株式会社 2024-10-15 CN disclosed
CN-118715251-A Curable composition, cured film, and display device 住友化学株式会社 2024-09-27 CN disclosed
CN-118661119-A Composition, light absorbing layer, laminate, and display device 住友化学株式会社 2024-09-17 CN disclosed
CN-118414380-A Composition, film and display device 住友化学株式会社 2024-07-30 CN disclosed
WO-2016057242-A1 HIF-2α INHIBITORS FOR TREATING IRON OVERLOAD DISORDERS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-04-14 WO disclosed
WO-2015035223-A1 ARYL ETHERS AND USES THEREOF PELOTON THERAPEUTICS, INC. (US) 2015-03-12 WO disclosed
EP-2593433-A2 N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS Pfizer Limited (GB) 2013-05-22 EP disclosed
EP-2593432-A1 N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS Pfizer Limited (GB) 2013-05-22 EP disclosed
EP-2593427-A1 SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN Pfizer Limited (GB) 2013-05-22 EP disclosed
WO-2013041106-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS 11CO FOR CARBONYLATION REACTIONS IN THE PREPARATION OF RADIOPHARMACEUTICALS FOR PET IMAGING AARHUS UNIVERSITET (DK) 2013-03-28 WO disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
WO-2012007883-A1 SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN PFIZER LIMITED (GB) 2012-01-19 WO disclosed
WO-2012007877-A2 CHEMICAL COMPOUNDS PFIZER LIMITED (GB) 2012-01-19 WO disclosed
WO-2012007861-A1 N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS PFIZER LIMITED (GB) 2012-01-19 WO disclosed