Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364082 | 0.78 | NPSR1 (0.46) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL28830916 | 0.77 | NPSR1 (0.50) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL29720879 | 0.76 | NPSR1 (0.45) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL25934782 | 0.75 | NPSR1 (0.41) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL2919515 | 0.75 | NPSR1 (0.48) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL547346 | 0.67 | HSD17B10 (0.51) | NPSR1HSD17B10KDM4EALDH1A1GPR17 | |
| SCHEMBL11406069 | 0.66 | KEAP1 (0.41) | NPSR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11020883 | 0.66 | — | — | |
| SCHEMBL394179 | 0.65 | — | — | |
| SCHEMBL7695445 | 0.64 | IMPDH2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144240-A1 | GLUCOSE SENSITIVE INSULIN DERIVATIVES AND USES THEREOF | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144545-A1 | SACCHARIDE SENSING SYSTEMS | Carbometrics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |