SCHEMBL3640852

SCHEMBL3640852

CN1C(C)(C)CC(C=CC(=O)O)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
UGT2B7 P16662 2/20 0.33
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9241314 1.00 TSHR (0.35) TSHRNFKB1CYP2C19THRBCYP2C9
SCHEMBL9063734 0.85 GAA (0.36) THRBCYP2C9UGT2B7APLNR
SCHEMBL10578285 0.81 THRB (0.32) THRBCYP2C9UGT2B7
Bicarbonate SCHEMBL28854272 0.81 TSHR (0.35) TSHRNFKB1CYP2C19APLNR
SCHEMBL5588475 0.78 ALDH1A1 (0.38) TSHRNFKB1CYP2C19
SCHEMBL6685009 0.75
SCHEMBL9240169 0.74 GAA (0.37) TSHRTHRBCYP2C9UGT2B7APLNR
SCHEMBL6247272 0.74 GAA (0.37) TSHRTHRBCYP2C9UGT2B7APLNR
SCHEMBL5588480 0.73 TSHR (0.33) TSHRNFKB1CYP2C19THRBCYP2C9
SCHEMBL96869 0.72 TSHR (0.34) TSHRNFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063544-A1 Copolymers of alpha-olefines containing sterically hindered amino groups CIBA-GEIGY AG (CH) 1982-10-27 EP claimed
CN-114957882-A PVC composition containing high molecular weight heat stabilizer and preparation method and application thereof 湖南联塑科技实业有限公司 2022-08-30 CN disclosed
CN-106800909-B Wafer laminate and method of manufacture 信越化学工业株式会社 2021-05-28 CN disclosed
EP-2164881-A1 USE OF SWELLABLE POLYMER FOR SEALING Evonik Röhm GmbH (DE) 2010-03-24 EP disclosed
WO-2009007154-A1 USE OF SWELLABLE POLYMER FOR SEALING EVONIK RÖHM GMBH (DE) 2009-01-15 WO disclosed
WO-2004033568-A1 ANTIMICROBIAL COATINGS AND METHOD FOR PRODUCTION THEREOF CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) 2004-04-22 WO disclosed
EP-0727205-B1 Thermoplastic coating and binder agent for pharmaceutical forms ROEHM GMBH (DE) 2001-05-30 EP disclosed
EP-0485840-B2 Pharmaceutical oral composition and coating agent containing a polysaccharide degradable in the colon ROEHM GMBH (DE) 1999-03-03 EP disclosed
EP-0727205-A2 Thermoplastic coating and binder agent for pharmaceutical forms RÖHM GMBH (DE) 1996-08-21 EP disclosed
EP-0526399-B1 Light-stabilized copolymer compositions as a binder in coating films CIBA GEIGY AG (CH) 1995-09-27 EP disclosed
EP-0542159-A1 Process for treating an aqueous pigment suspension with an aqueous binder agent RÖHM GMBH (DE) 1993-05-19 EP disclosed
EP-0417570-B1 AQUEOUS POLYACRYLAT-DISPERSION AS HOT-MELTING ADHESIVE RÖHM GMBH (DE) 1993-02-10 EP disclosed
EP-0526399-A2 Light-stabilized copolymer compositions as a binder in coating films CIBA-GEIGY AG (CH) 1993-02-03 EP disclosed
EP-0417588-B1 PROCESS FOR THE PREPARATION OF A COMPLEXED DRUG RÖHM GMBH (DE) 1992-08-19 EP disclosed
EP-0485840-A2 Pharmaceutical oral composition and coating agent containing a polysaccharide degradable in the colon RÖHM GMBH (DE) 1992-05-20 EP disclosed
EP-0441746-A2 Light-stabilised binding agent for coatings CIBA-GEIGY AG (CH) 1991-08-14 EP disclosed
EP-0417570-A1 Aqueous polyacrylat-dispersion as hot-melting adhesive RÖHM GMBH (DE) 1991-03-20 EP disclosed
EP-0417588-A2 Process for the preparation of a complexed drug RÖHM GMBH (DE) 1991-03-20 EP disclosed
EP-0376094-A2 Process for hardening an injection agent RÖHM GMBH (DE) 1990-07-04 EP disclosed
EP-0114784-A2 Electron-beam curing method for coatings CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed