Mandelic Acid

Mandelic Acid

SCHEMBL3644

C=N.O=C(O)C(O)c1ccccc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.86
MAPK1 P28482 1/20 0.86
CES2 O00748 2/20 0.56
CES1 P23141 2/20 0.56
HPGD P15428 1/20 0.55
SRC P12931 2/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.44
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN7 P35236 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
ESR2 Q92731 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL28877698 0.93 LMNA (0.90) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL21647917 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL165161 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL5313046 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL255601 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL1050 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL29777368 0.93 LMNA (1.00) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL3934174 0.90 LMNA (0.95) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL1374278 0.90 LMNA (0.95) LMNAMAPK1CES2CES1HPGD
Mandelic Acid SCHEMBL9185770 0.90 LMNA (0.95) LMNAMAPK1CES2CES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3940 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 US claimed
EP-3965771-A1 FINISHED PHARMACEUTICAL DOSAGE FORM OF A METHENAMINE SALT SUCH AS METHENAMINE MANDELATE Edenbridge Pharmaceuticals, LLC (US) 2022-03-16 EP claimed
EP-3912989-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) 2021-11-24 EP claimed
US-20210322424-A1 Finished Pharmaceutical Dosage Form Of A Methenamine Salt Such As Methenamine Mandelate Edenbridge Pharmaceuticals, LLC (US) 2021-10-21 US claimed
WO-2021112914-A1 FINISHED PHARMACEUTICAL DOSAGE FORM OF A METHENAMINE SALT SUCH AS METHENAMINE MANDELATE Edenbridge Pharmaceuticals, LLC (US) 2021-06-10 WO claimed
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
EP-3464290-B1 PROCESSES FOR PRODUCING METHENAMINE MANDELATE ALBEMARLE CORP (US) 2020-12-16 EP claimed
US-10683303-B2 Processes for producing methenamine mandelate ALBEMARLE CORPORATION (US) 2020-06-16 US claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
WO-1993024154-A1 BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM FUISZ TECHNOLOGIES, LTD. (US) 1993-12-09 WO claimed
US-5171563-A Cleavable linkers for the reduction of non-target organ retention of immunoconjugates NEORX CORPORATION (US) 1992-12-15 US claimed
EP-0436664-A4 CLEAVABLE LINKERS FOR THE REDUCTION OF NON-TARGET ORGAN RETENTION OF IMMUNOCONJUGATES 1992-04-22 EP claimed
EP-0436664-A1 CLEAVABLE LINKERS FOR THE REDUCTION OF NON-TARGET ORGAN RETENTION OF IMMUNOCONJUGATES. NEORX CORP (US) 1991-07-17 EP claimed
US-4601880-A POLYMER, FORMALDEHYDE RELEASING COMPOUND ALZA CORPORATION (US) 1986-07-22 US claimed
US-4464258-A METHENAMINE ALZA CORPORATION (US) 1984-08-07 US claimed
US-4288543-A SAMPLING IN LIQUID PHASE WITH ANTIGROWTH AGENTS-BIOLOGICAL PFIZER INC. (US) 1981-09-08 US claimed
US-4241195-A COATING OF FORMAMIDINESULFINIC ACID, METHENAMINE MANDELATE, IN RESINOUS CARRIER WESTINGHOUSE ELECTRIC CORP. (US) 1980-12-23 US claimed
US-4149161-A Protecting electrical apparatus with gas generating compounds WESTINGHOUSE ELECTRIC CORP. (US) 1979-04-10 US claimed