SCHEMBL36452

SCHEMBL36452

[CH2]c1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.48
CYP1A2 P05177 5/20 0.48
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 4/20 0.48
HSD17B10 Q99714 4/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ALOX12 P18054 2/20 0.47
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
HPGD P15428 2/20 0.41
GSTP1 P09211 1/20 0.41
RELA Q04206 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27838385 0.97 CYP2A6 (0.46) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL27905829 0.97 CYP2A6 (0.46) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL536732 0.92 ALDH1A1 (0.50) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL2463315 0.92 ALDH1A1 (0.50) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL27922290 0.90 CYP2A6 (0.46) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL21644746 0.90 CYP2A6 (0.46) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL1178667 0.87 CYP2A6 (0.37) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
SCHEMBL1971137 0.79 ALDH1A1 (0.61) CYP2A6CYP1A2ALDH1A1HSD17B10TDP1
SCHEMBL7409541 0.79 ESR1 (0.61) CYP1A2ALDH1A1CA1CA2CA9
SCHEMBL6313887 0.78 ESR1 (0.57) CYP1A2ALDH1A1CYP3A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18561 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302451-A Novel oligosaccharide, intermediate for producing the oligosaccharide, and process for producing the same 第一三共株式会社 2024-07-05 CN claimed
WO-2024140063-A1 THIOXANTHENE SULFONIUM SALT PHOTOINITIATOR AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
US-20240218022-A1 ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-04 US claimed
WO-2024140062-A1 THIOXANTHENIUM SALT PHOTOINITIATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
CN-118271331-A Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation 赣江中药创新中心 2024-07-02 CN claimed
CN-118271281-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-118271280-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-118047824-B Use of dialkylphosphonic acids in oligonucleotide synthesis 北京瑞博奥医药科技有限公司 2024-06-28 CN claimed
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
US-12018306-B2 Method for chemically synthesizing Helicobacter pylori core lipopolysaccharide oligosaccharide antigen carbohydrate chain JIANGNAN UNIVERSITY (CN) 2024-06-25 US claimed
EP-0065407-A2 Pharmaceutical spiro-succinimide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-11-24 EP claimed
US-4348264-A Photocatalyzed process for producing carbapenams and carbapen-2-ems PFIZER INC. (US) 1982-09-07 US claimed
EP-0054862-A1 Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase SCHERING CORPORATION (US) 1982-06-30 EP claimed
EP-0040494-A1 Carbapenams and carbapen-2-ems and process therefor PFIZER INC. (US) 1981-11-25 EP claimed
EP-0028906-A1 1'-Substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones, processes for their manufacture and pharmaceutical compositions thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-20 EP claimed
US-4265819-A Preparation of dihalogenovinylcyclopropanecarboxylic acids and esters BAYER AKTIENGESELLSCHAFT (DE) 1981-05-05 US claimed
US-4217300-A Preparation of dihalogenovinylcyclopropanecarboxylic acids and esters BAYER AKTIENGESELLSCHAFT (DE) 1980-08-12 US claimed
US-4097598-A Quaternary salts as hypoglycemic agents PFIZER INC. (US) 1978-06-27 US claimed
US-4044015-A Imidazopyridinium compounds as hypoglycemic agents PFIZER INC. (US) 1977-08-23 US claimed
US-4021542-A Derivatives of hydrazino-monosaccharides and aldohexoses which are useful as intermediates for preparing compounds or as compounds which lower the uric acid BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-05-03 US claimed