Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536732 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL36452 | 0.92 | CYP2A6 (0.48) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL27905829 | 0.89 | CYP2A6 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL27838385 | 0.89 | CYP2A6 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL1178667 | 0.85 | CYP2A6 (0.37) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL28217476 | 0.85 | ALOX5 (0.40) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL27922290 | 0.82 | CYP2A6 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| SCHEMBL21644746 | 0.82 | CYP2A6 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| Benz(B)Anthracene SCHEMBL3474922 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A | |
| Benz(B)Anthracene SCHEMBL22352910 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230641-A1 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC,. | 2011-09-22 | — | — | US | claimed |
| WO-2010068371-A2 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | claimed |
| US-8580998-B2 | Preparation of alkenes by mild thermolysis of sulfoxides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110230641-A1 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC,. | 2011-09-22 | — | — | US | disclosed |
| WO-2010068371-A2 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230641-A1 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | PTMS, DNPEP, SRMS | ALDH1A1 783/4885HSD17B10 1323/4885TDP1 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.