Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022695 | 0.88 | AKR1C3 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3645882 | 0.84 | ALDH1A1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL135801 | 0.84 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9822535 | 0.83 | NR4A1 (0.59) | ALDH1A1MAPTCES2CES1 | |
| Hydrochloric Acid SCHEMBL3893485 | 0.83 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL533002 | 0.83 | BCAT2 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6105501 | 0.83 | KDM4E (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28670609 | 0.81 | CA1 (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10335857 | 0.80 | LMNA (0.58) | MMP2ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL28005990 | 0.79 | CA1 (0.47) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |
| US-4924014-A | Process for the preparation of halogen-containing aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |