SCHEMBL27799698

SCHEMBL27799698

O=C(Cl)c1cccc(S(=O)(=O)Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 2/20 0.39
TSHR P16473 3/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 2/20 0.37
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
TRPV4 Q9HBA0 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CA5A P35218 1/20 0.33
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28253353 0.90 ALOX15 (0.33) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL10586122 0.85 ALDH1A1 (0.39) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL6153587 0.85 TSHR (0.57) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL24458009 0.83 TSHR (0.37) ALOX15TSHRCA1CA2CA9
SCHEMBL28176076 0.83 BCAT2 (0.44) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL10589856 0.83 CA2 (0.51) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL3645882 0.82 ALDH1A1 (0.48) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL628149 0.81 ALDH1A1 (0.42) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL12569842 0.79 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRCA1CA2
SCHEMBL27955539 0.79 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531654-A The method for preparing dicarboxylic acid compound 第三共株式会社 2018-01-02 CN claimed
CN-109232442-A Acceptable salt, preparation method, herbicidal composition on aryi-uracile class compound or its Pesticide Science 深圳大学 2019-01-18 CN disclosed
CN-104470626-B Composite polyamide membranes with increased carboxylic acid functionality 陶氏环球技术有限责任公司 2018-06-01 CN disclosed
CN-105189453-B Sulfamoyl aryl amide and its purposes as the medicine for treating hepatitis B 爱尔兰詹森科学公司 2018-04-10 CN disclosed
CN-107771176-A The inhibitor of human immunodeficiency virus replication VIIV保健英国第五有限公司 2018-03-06 CN disclosed
CN-107531654-A The method for preparing dicarboxylic acid compound 第三共株式会社 2018-01-02 CN disclosed
CN-104352492-B Extend enzyme inhibitor using arylsulfonyl derivatives as the long chain fatty acids of active ingredient MSD K.K.公司 2017-12-05 CN disclosed
CN-107337621-A Dicarboxylic acid compound 第三共株式会社 2017-11-10 CN disclosed
CN-107311895-A Dicarboxylic acid compound 第三共株式会社 2017-11-03 CN disclosed
CN-107207467-A 2, 4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG 癌症研究科技有限公司 2017-09-26 CN disclosed
CN-104487160-A Structurally improved composite polyamide membranes DOW GLOBAL TECHNOLOGIES LLC 2015-04-01 CN disclosed
CN-104470629-A Films derived from multifunctional amines and combinations of different multifunctional amine-reactive monomers DOW GLOBAL TECHNOLOGIES INC 2015-03-25 CN disclosed
CN-104470626-A Composite polyamide membranes with increased carboxylic acid functionality DOW GLOBAL TECHNOLOGIES INC 2015-03-25 CN disclosed
CN-101877966-A Farnesoid X receptor agonists SMITHKLINE BEECHAM CORP 2010-11-03 CN disclosed