Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL28062049 | 0.90 | TYR (0.52) | TYRCYP2D6KDM4EMAPK1KMT2A | |
| Isopropylbenzene SCHEMBL27707501 | 0.87 | TYR (0.50) | TYRCYP2D6KDM4EMAPK1KMT2A | |
| Isopropylbenzene SCHEMBL28285501 | 0.87 | TYR (0.50) | TYRCYP2D6KDM4EMAPK1KMT2A | |
| Isopropylbenzene SCHEMBL28324070 | 0.87 | TYR (0.50) | TYRCYP2D6KDM4EMAPK1KMT2A | |
| Isopropylbenzene SCHEMBL27303816 | 0.87 | TYR (0.50) | TYRCYP2D6KDM4EMAPK1KMT2A | |
| Acetaldehyde SCHEMBL27727291 | 0.86 | PTGS2 (0.53) | TYRKMT2ALMNAMAPT | |
| Isopropylbenzene SCHEMBL11254813 | 0.86 | — | — | |
| Isopropylbenzene SCHEMBL87809 | 0.86 | TAAR1 (0.50) | CYP2D6KDM4ETAAR1ALDH1A1HIF1A | |
| Isopropylbenzene SCHEMBL8431863 | 0.86 | TAAR1 (0.50) | CYP2D6KDM4ETAAR1ALDH1A1HIF1A | |
| Isopropylbenzene SCHEMBL6568 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792795-B | Improvement relevant to the beneficial agent of encapsulating | 荷兰联合利华有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-101669887-B | Hair processing agent and method for permanent waving hair | SHOWA DENKO KK | 2012-12-05 | — | — | CN | disclosed |
| CN-101083975-B | Hair treatment agent and hair waving method | SHOWA DENKO KK | 2010-12-01 | — | — | CN | disclosed |
| EP-2194954-A2 | PERSONAL CARE COMPOSITIONS CONTAINING SILICONE-ORGANIC GELS FROM POLYALKYLOXYLENE CROSSLINKED SILICONE ELASTOMERS | Dow Corning Corporation (US) | 2010-06-16 | — | — | EP | disclosed |
| CN-101669887-A | Hair processing agent and method for permanent waving hair | SHOWA DENKO KK | 2010-03-17 | — | — | CN | disclosed |
| EP-2114366-A2 | PERSONAL CARE COMPOSITIONS CONTAINING SILICONE ELASTOMER GELS | Dow Corning Corporation (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009042832-A2 | PERSONAL CARE COMPOSITIONS CONTAINING SILICONE-ORGANIC GELS FROM POLYALKYLOXYLENE CROSSLINKED SILICONE ELASTOMERS | DOW CORNING CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |
| EP-2001934-A2 | SILICONE-ORGANIC ELASTOMER GELS | Dow Corning Corporation (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2008085360-A2 | PERSONAL CARE COMPOSITIONS CONTAINING SILICONE ELASTOMER GELS | DOW CORNING CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |
| CN-101083975-A | Hair treatment agent and hair waving method | SHOWA DENKO KK (JP) | 2007-12-05 | — | — | CN | disclosed |
| WO-2007109282-A2 | SILICONE-ORGANIC ELASTOMER GELS | DOW CORNING CORPORATION (US) | 2007-09-27 | — | — | WO | disclosed |
| US-7211680-B2 | Vitamin D derivatives with carbo-or heterocyclic substituents at C-25, a process for their production, intermediate products and their use for producing medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20050080058-A1 | New vitamin D derivatives with carbo-or heterocyclic substituents at C-25, a process for their production, intermediate products and their use for producing medicaments | SCHERING AKTIENGESELLSCHAFT PATENTS (DE) | 2005-04-14 | — | — | US | disclosed |
| US-6642218-B2 | (5Z,7E,22E)-(1S,3R,24R)-25-(5-Propyloxazol-2-yl)-26,27-cyclo -9,10-secocholesta-5,7,10(19), 22-tetraene-1,3,24-triol for treatment of diseases characterized by hyperproliferation and deficient cell differentiation | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-11-04 | — | — | US | disclosed |
| US-20020049344-A1 | NEW VITAMIN D DERIVATIVES WITH CARBO-OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049344-A1 | NEW VITAMIN D DERIVATIVES WITH CARBO-OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS | CYP2R1, VDR, CYP24A1 | TYR 1017/4885CYP2D6 265/4885KDM4E 3877/4885 |
| US-20050080058-A1 | New vitamin D derivatives with carbo-or heterocyclic substituents at C-25, a process for their production, intermediate products and their use for producing medicaments | VDR, CYP24A1, CYP2R1 | TYR 850/4885CYP2D6 581/4885KDM4E 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.