Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 9/20 | 0.54 |
| ▸ | CTRC | Q99895 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561782 | 0.98 | MPL (0.55) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL11528715 | 0.87 | AURKA (0.49) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL303533 | 0.83 | CYP1A2 (0.53) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL3647906 | 0.83 | DUSP5 (0.50) | MPLCTRCMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL19999157 | 0.81 | MPL (0.47) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL20138548 | 0.81 | MPL (0.50) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL2018837 | 0.79 | MPL (0.51) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL11527283 | 0.78 | TNNI3 (0.48) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL15692263 | 0.78 | AURKA (0.49) | MPLCTRCMAPK1ALDH1A1AURKA | |
| SCHEMBL18205264 | 0.78 | AURKA (0.49) | MPLCTRCALDH1A1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078714-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED, INC. (US) | 2016-10-12 | — | — | EP | disclosed |
| EP-2181160-B1 | HPTS-MONO CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED INC (US) | 2016-05-11 | — | — | EP | disclosed |
| US-8202731-B2 | HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100279424-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-7824918-B2 | HPTS-Mono and BIS Cys-Ma polymerizable fluorescent dyes for use in analyte sensors | GLUMETRICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-2181160-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | Glumetrics, Inc. (US) | 2010-05-05 | — | — | EP | disclosed |
| US-20090061528-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2009-03-05 | — | — | US | disclosed |
| WO-2009021057-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279424-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | PTMS, PFAS, HMBS | MPL 3303/4885CTRC 885/4885MAPK1 4421/4885 |
| US-20090061528-A1 | HPTS-MONO AND BIS CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | PTMS, PFAS, HMBS | MPL 3303/4885CTRC 885/4885MAPK1 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.