Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921526 | 0.96 | SMN1; SMN2 (0.51) | SMN1; SMN2HRH3TAAR1TBXA2RHSD11B1 | |
| SCHEMBL14921525 | 0.96 | SMN1; SMN2 (0.51) | SMN1; SMN2HRH3TAAR1TBXA2RHSD11B1 | |
| SCHEMBL14921524 | 0.96 | SMN1; SMN2 (0.51) | SMN1; SMN2HRH3TAAR1TBXA2RHSD11B1 | |
| SCHEMBL4608144 | 0.84 | SLC9A1 (0.50) | HRH3SLC9A1SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL12592455 | 0.83 | KCNQ3 (0.53) | HRH3SLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL4522521 | 0.83 | KCNQ3 (0.53) | HRH3SLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL839092 | 0.83 | KCNQ3 (0.53) | HRH3SLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL7352063 | 0.83 | KCNQ3 (0.53) | HRH3SLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL7352068 | 0.83 | KCNQ3 (0.53) | HRH3SLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL7191194 | 0.83 | SLC6A2 (0.48) | HRH3SLC9A1SLC6A2SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| CN-101743223-A | Novel compounds as cannabinoid receptor ligands | ABBOTT LAB | 2010-06-16 | — | — | CN | disclosed |
| EP-2176219-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2009009550-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | WO | disclosed |
| CN-1972910-A | Lactam tachykinin receptor antagonists | MERCK & CO INC (US) | 2007-05-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | SMN1; SMN2 3100/4885HRH3 85/4885TAAR1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.