Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770096 | 0.91 | RAB9A (0.50) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL904248 | 0.87 | CTBP2 (0.60) | NPC1RAB9AHTTLMNAHIF1A | |
| SCHEMBL30342076 | 0.87 | CTBP2 (0.60) | NPC1RAB9AHTTLMNAHIF1A | |
| SCHEMBL7194988 | 0.85 | NPC1 (0.69) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL571063 | 0.84 | USP2 (0.69) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL248073 | 0.81 | NPC1 (0.73) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL1515775 | 0.80 | MEN1 (0.61) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL1983304 | 0.80 | LMNA (0.54) | NPC1HTTSMN1; SMN2LMNATP53 | |
| Methoxymethane SCHEMBL27486318 | 0.80 | MAPT (0.63) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL23906975 | 0.79 | NPC1 (0.62) | NPC1RAB9AHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | claimed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | claimed |
| US-8480662-B2 | Systems and devices for photoablation | CARDIAC PACEMAKERS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2188014-A1 | SYSTEMS AND DEVICES FOR PHOTOABLATION | Cardiac Pacemakers, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009025826-A1 | SYSTEMS AND DEVICES FOR PHOTOABLATION | CARDIAC PACEMAKERS, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| US-20090054883-A1 | Systems and devices for photoablation | CARDIAC PACEMAKERS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5767288-A | DITHIANE-BENZOIN ADDUCTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0700378-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0700378-A4 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 1996-01-22 | — | — | EP | disclosed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | disclosed |
| WO-1994027957-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-08 | — | — | WO | disclosed |