Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366338 | 0.90 | NR4A2 (0.45) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL364927 | 0.88 | SRC (0.51) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL366111 | 0.87 | LMNA (0.52) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL366941 | 0.85 | ALDH1A1 (0.46) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL364339 | 0.85 | KMT2A (0.49) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL364281 | 0.85 | NR4A2 (0.48) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL367527 | 0.84 | NR4A2 (0.41) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL364265 | 0.83 | NR4A2 (0.46) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL364450 | 0.83 | KMT2A (0.47) | NR4A2KMT2AKDM4EMEN1EGFR | |
| SCHEMBL366488 | 0.82 | NR4A2 (0.45) | NR4A2KMT2AKDM4EMEN1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |