Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364443 | 0.87 | ALDH1A1 (0.45) | MAPTL3MBTL1TSHRALDH1A1MEN1 | |
| SCHEMBL365044 | 0.86 | KMT2A (0.47) | PDK2MAPTL3MBTL1TSHRALDH1A1 | |
| SCHEMBL366448 | 0.85 | GPR119 (0.38) | MAPTL3MBTL1TSHRALDH1A1GPR119 | |
| SCHEMBL364883 | 0.84 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL364990 | 0.82 | ALDH1A1 (0.36) | MAPTL3MBTL1TSHRALDH1A1MEN1 | |
| SCHEMBL366450 | 0.82 | SMN1; SMN2 (0.46) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL366244 | 0.82 | PSEN1 (0.41) | MAPTL3MBTL1TSHRALDH1A1MEN1 | |
| SCHEMBL365607 | 0.82 | ALDH1A1 (0.35) | MAPTL3MBTL1TSHRALDH1A1MEN1 | |
| SCHEMBL366164 | 0.81 | TSHR (0.39) | MAPTL3MBTL1TSHRALDH1A1MEN1 | |
| SCHEMBL367540 | 0.81 | PSEN1 (0.45) | MAPTL3MBTL1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |