Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366931 | 0.92 | CNR1 (0.42) | ALDH1A1KMT2AHPGD | |
| SCHEMBL365979 | 0.86 | ALDH1A1 (0.36) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL366275 | 0.86 | ALDH1A1 (0.36) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL364902 | 0.86 | ALDH1A1 (0.40) | TSHRALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL365753 | 0.85 | ALDH1A1 (0.35) | TSHRALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL366244 | 0.85 | PSEN1 (0.41) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL365061 | 0.85 | KMT2A (0.49) | TSHRALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL364749 | 0.84 | ESR1 (0.38) | TSHRALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL366164 | 0.84 | TSHR (0.39) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL367540 | 0.84 | PSEN1 (0.45) | TSHRALDH1A1CYP1A2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |