Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365062 | 0.92 | TSHR (0.42) | ALDH1A1HPGDKMT2A | |
| SCHEMBL366930 | 0.86 | ALDH1A1 (0.47) | CNR1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL365361 | 0.84 | PPARG (0.49) | CNR1ALDH1A1KDM4EGAA | |
| SCHEMBL365979 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL366275 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL364902 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL366244 | 0.83 | PSEN1 (0.41) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL365753 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL366794 | 0.82 | PSEN1 (0.36) | ALDH1A1KDM4ELMNAKMT2AGAA | |
| SCHEMBL366164 | 0.82 | TSHR (0.39) | ALDH1A1KDM4EHPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |