Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650821 | 0.85 | CNR1 (0.45) | CNR2CNR1 | |
| SCHEMBL3450091 | 0.82 | ALDH1A1 (0.46) | CNR2CNR1NPSR1MAPTLMNA | |
| SCHEMBL3376301 | 0.79 | LMNA (0.49) | CNR2CNR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL3843011 | 0.79 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL4737409 | 0.78 | CNR2 (0.39) | CNR2CNR1NPSR1MAPTLMNA | |
| SCHEMBL3339082 | 0.78 | KDM4E (0.43) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL13834657 | 0.73 | POLB (0.52) | CNR2NPSR1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3816429 | 0.73 | PARP1 (0.37) | CNR2CNR1MAPTKMT2AMEN1 | |
| SCHEMBL3483096 | 0.73 | CREBBP (0.48) | CNR2CNR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL3483080 | 0.73 | CREBBP (0.48) | CNR2CNR1SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197875-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-06-23 | — | — | EP | claimed |
| WO-2009037222-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | WO | claimed |
| EP-2197875-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009037222-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | WO | disclosed |