Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348939 | 0.71 | FFAR1 (0.43) | FFAR1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL351084 | 0.71 | FFAR1 (0.43) | FFAR1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL9424247 | 0.69 | ALDH1A1 (0.67) | FFAR1ALDH1A1GAAL3MBTL1ACHE | |
| SCHEMBL9718462 | 0.67 | FFAR1 (0.61) | FFAR1ALDH1A1GAAL3MBTL1FFAR4 | |
| SCHEMBL6515606 | 0.66 | FFAR1 (0.56) | FFAR1ALDH1A1FFAR4TSHRSTAT3 | |
| SCHEMBL11332403 | 0.65 | FFAR1 (0.62) | FFAR1ALDH1A1FFAR4TSHRSTAT3 | |
| SCHEMBL351929 | 0.65 | CASP3 (0.42) | FFAR1L3MBTL1TSHR | |
| SCHEMBL349358 | 0.65 | CASP3 (0.42) | FFAR1L3MBTL1TSHR | |
| SCHEMBL8476326 | 0.64 | FFAR1 (0.53) | FFAR1ALDH1A1GAAL3MBTL1FFAR4 | |
| SCHEMBL25152959 | 0.64 | ACHE (0.67) | FFAR1ALDH1A1TSHRSTAT3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009646-A1 | METHODS OF TREATING FRAGILE X SYNDROME, DOWN'S SYNDROME, AUTISM AND RELATED DISORDERS | XENOPORT, INC. (US) | 2012-01-19 | — | — | WO | claimed |