Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365378 | 0.89 | KMT2A (0.45) | HTR5AADAM17KMT2AALDH1A1KDM4E | |
| SCHEMBL366450 | 0.88 | SMN1; SMN2 (0.46) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL364443 | 0.86 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL364990 | 0.84 | ALDH1A1 (0.36) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL365607 | 0.84 | ALDH1A1 (0.35) | KMT2AALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL364938 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL366268 | 0.83 | SMN1; SMN2 (0.37) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL364883 | 0.82 | ALDH1A1 (0.41) | KMT2AALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL366244 | 0.81 | PSEN1 (0.41) | KMT2AALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL366164 | 0.80 | TSHR (0.39) | KMT2AALDH1A1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |