Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366450 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AATM | |
| SCHEMBL366267 | 0.88 | KMT2A (0.45) | SMN1; SMN2ALDH1A1ACHEBCHEMEN1 | |
| SCHEMBL364938 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1ACHEBCHEMAOB | |
| SCHEMBL364443 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL365377 | 0.83 | HTR5A (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL364990 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL364883 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL365607 | 0.82 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL367540 | 0.80 | PSEN1 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL364749 | 0.80 | ESR1 (0.38) | SMN1; SMN2ALDH1A1MEN1KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |