Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | RHOC | P08134 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659526 | 0.93 | F2 (0.46) | F2RHOCRHOADRD2DRD3 | |
| SCHEMBL3662481 | 0.93 | F2 (0.37) | F2RHOCRHOADRD2DRD3 | |
| SCHEMBL3660828 | 0.91 | RHOC (0.47) | F2RHOCRHOACCR2 | |
| SCHEMBL3661726 | 0.91 | CCR2 (0.39) | F2DRD2DRD3CCR2POLB | |
| SCHEMBL3658255 | 0.90 | F2 (0.36) | F2RHOCRHOADRD2DRD3 | |
| SCHEMBL3662128 | 0.85 | TSHR (0.35) | POLBALDH1A1 | |
| SCHEMBL3656419 | 0.84 | NPC1 (0.35) | F2NPC1RAB9A | |
| SCHEMBL3656172 | 0.84 | F2 (0.46) | F2DRD2DRD3KMT2A | |
| SCHEMBL3659731 | 0.83 | F2 (0.38) | F2DRD2DRD3KMT2A | |
| SCHEMBL3655106 | 0.83 | F2 (0.38) | F2RHOCRHOADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234966-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Sanofi-Aventis (FR) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009106708-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | disclosed |